PDCL - phosducin like Gene

Also Known as PhLP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5082

About PDCL

Cytogenetic location: 9q33.2 Genomic coordinates (GRCh38): 9:122,818,097-122,828,588 (from NCBI)

This gene has 3 transcripts (splice variants), 201 orthologues and 4 paralogues. Ubiquitous expression in endometrium (RPKM 5.5), lung (RPKM 5.2) and 25 other tissues.

Summary

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]

PDCL Products (1)

mRNA Protein Name
NM_005388.5 NP_005379.3 phosducin-like protein

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21516116 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PDCL Protein Structure

Phosducin

Phosducin: Phosducin (36 - 299)

  • 0
  • 100
  • 200
  • 301 a.a.
Protein Preferred Names Protein Names

phosducin-like protein

PDCL Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PDCL Q13371 ATN1 Homo sapiens Q86V38
Validated Y2H
32814053
Intra
PDCL Q13371 ATN1 Homo sapiens Q86V38
Y2H Array
32814053
Intra
PDCL Q13371 ATN1 Homo sapiens Q86V38
Y2H Pooling
32814053
Intra
PDCL Q13371 PSMC5 Homo sapiens P62195
Lumier
32814053
Intra
PDCL Q13371 PSMC5 Homo sapiens P62195
Y2H
21516116
Intra
PDCL Q13371 PSMC5 Homo sapiens P62195
Y2H Array
29892012
Intra
PDCL Q13371 MRPL11 Homo sapiens Q9Y3B7
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

PDCL Antibodies

Cat. No. Product Name Application Reactivity
HY-P89727 PhLP Antibody (YA9071) WB, ICC/IF, IF-Tissue, IP, ELISA human

Related Diseases

Diseases Alias
Pollen Allergy

  • Hay Fever
Timothy Grass Allergy
Thunderstorm Triggered Asthma

  • Thunderstorm Asthma

  • Thunderstorm Related Asthma
Tomato Allergy

  • Solanum Lycopersicum Fruit Allergy
Melon Allergy

  • Cucumis Melo Fruit Allergy
Orange Allergy

  • Citrus Sinensis Fruit Allergy
Apple Allergy

  • Malus Domestica Fruit Allergy
Peach Allergy

  • Prunus Persica Fruit Allergy
Vegetable Allergy
Latex Allergy
Fruit Allergy

  • Allergy To Fruit
Fish Allergy

  • Allergy To Fish
Crustacean Allergy
Shrimp Allergy
Respiratory Allergy

  • Airway Allergy
Legume Allergy

  • Fabaceae Allergy
Wheat Allergy

  • Wheat Allergic Reaction

  • Wheat Hypersensitivity

  • Allergy To Wheat

  • Allergy Wheat
Nut Allergy

  • Nut Allergic Reaction

  • Nut Hypersensitivity

  • Allergy To Nuts

  • Allergy Nut
Nasal Cavity Disease

  • Disorder Of Nasal Cavity
Peanut Allergy

  • Allergy To Peanuts

  • Peanut Allergic Reaction

  • Allergies Peanut

  • Peanut Hypersensitivity
Nose Disease

  • Nose Diseases

  • Disorder Of The Nose

  • Nasal Disorder

  • Abnormality Of The Nose
Celery Allergy
Vernal Conjunctivitis

  • Conjunctivitis Vernal

  • Conjunctivitis, Vernal
Egg Allergy

  • Allergy To Eggs

  • Allergies Egg

  • Egg Hypersensitivity
Status Asthmaticus

  • Asthma With Status Asthmaticus

  • Severe Asthma Attack
Chronic Rhinitis

  • Rhinitis - Chronic

  • Chronic Rhinitis Nos

  • Rhinitis

  • Rhinitis Nos
Food Allergy

  • Food Hypersensitivity

  • Food Allergies

  • Allergy Food

  • Food Allergen-Induced Hypersensitivity
Intermittent Asthma
Conjunctival Disease

  • Conjunctival Diseases

  • Conjunctival Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W010686 PdCl2(Amphos)2 98.10% Unkown
HY-D1244 CO probe 1 99.88% Unkown
HY-RS10196 PDCL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10197 PDCL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10198 PDCL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta PDCL VGNC VGNC:75907
Mus musculus PDCL MGD MGI:1914716
Felis catus PDCL VGNC VGNC:68750
Canis familiaris PDCL VGNC VGNC:44342
Rattus norvegicus PDCL RGD RGD:621135
Bos taurus PDCL VGNC VGNC:32665
Others PDCL NCBI