2. Gene
  3. SS18L2 - SS18 like 2 Gene

SS18L2 - SS18 like 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as KIAA-iso

Gene ID: 51188 | Gene type: protein coding

About SS18L2

Cytogenetic location: 3p22.1 Genomic coordinates (GRCh38): 3:42,581,840-42,596,934 (from NCBI)

This gene has 3 transcripts (splice variants), 202 orthologues and 2 paralogues. Ubiquitous expression in lymph node (RPKM 8.2), prostate (RPKM 6.4) and 25 other tissues.

Summary

Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L2 gene is homologous to SS18.[supplied by OMIM, Jul 2002]

SS18L2 Products(2)

mRNA Protein Name
NM_001370300.1 NP_001357229.1 SS18-like protein 2
NM_016305.4 NP_057389.1 SS18-like protein 2

SS18L2 Protein Structure

SSXT

SSXT: SSXT protein (N-terminal region) (11 - 75)

  • 0
  • 77 a.a.
Protein Preferred Names Protein Names

SS18-like protein 2

SYT homolog 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13803 SS18L2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris SS18L2 VGNC VGNC:46825
Rattus norvegicus SS18L2 RGD RGD:1590139
Felis catus SS18L2 VGNC VGNC:102850
Mus musculus SS18L2 MGD MGI:1349474