ARMCX1 - armadillo repeat containing X-linked 1 Gene

Also Known as ALEX1; GASP7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51309

About ARMCX1

Cytogenetic location: Xq22.1 Genomic coordinates (GRCh38): X:101,550,547-101,554,700 (from NCBI)

This gene has 1 transcript (splice variant), 153 orthologues and 11 paralogues. Ubiquitous expression in ovary (RPKM 26.3), adrenal (RPKM 20.2) and 24 other tissues.

Summary

This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with Other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq, Jul 2008]

ARMCX1 Products (1)

mRNA Protein Name
NM_016608.2 NP_057692.1 armadillo repeat-containing X-linked protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

armadillo repeat-containing X-linked protein 1

  • ARM protein lost in epithelial cancers on chromosome X 1

ARMCX1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ARMCX1 Q9P291 TFIP11 Homo sapiens Q9UBB9
Y2H Array
31515488
Intra
ARMCX1 Q9P291 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
25416956
Intra
ARMCX1 Q9P291 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
ARMCX1 Q9P291 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
ARMCX1 Q9P291 ZBTB8A Homo sapiens Q96BR9
Validated Y2H
25416956
Intra
ARMCX1 Q9P291 ZBTB8A Homo sapiens Q96BR9
Y2H Array
32296183
Intra
ARMCX1 Q9P291 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
25416956
Intra
ARMCX1 Q9P291 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
32296183
Intra
ARMCX1 Q9P291 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
ARMCX1 Q9P291 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
ARMCX1 Q9P291 COIL Homo sapiens P38432
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01007 ARMCX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ARMCX1 VGNC VGNC:54659
Bos taurus ARMCX1 VGNC VGNC:50546
Rattus norvegicus ARMCX1 RGD RGD:1561629
Mus musculus ARMCX1 MGD MGI:1925498
Others ARMCX1 NCBI