IL20RA - interleukin 20 receptor subunit alpha Gene

Homo sapiens

Also known as CRF2-8; IL-20R1; IL-20RA; IL-20R-alpha

Gene ID: 53832 | Gene type: protein coding

About IL20RA

Cytogenetic location: 6q23.3 Genomic coordinates (GRCh38): 6:136,999,971-137,044,965 (from NCBI)

This gene has 8 transcripts (splice variants), 196 orthologues and 11 paralogues. Biased expression in skin (RPKM 13.8), adrenal (RPKM 3.9) and 13 other tissues.

Summary

This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

IL20RA Products(4)

mRNA	Protein	Name
NM_001278722.2	NP_001265651.2	interleukin-20 receptor subunit alpha isoform 2
NM_001278723.3	NP_001265652.2	interleukin-20 receptor subunit alpha isoform 3
NM_001278724.4	NP_001265653.2	interleukin-20 receptor subunit alpha isoform 4
NM_014432.4	NP_055247.4	interleukin-20 receptor subunit alpha isoform 1 precursor

IL20RA Protein Structure

Tissue_fac

Interfer-bind

0
100
200
300
400
500
553 a.a.

Protein Preferred Names

Protein Names

interleukin-20 receptor subunit alpha

class II cytokine receptor ZCYTOR7

Recombinant IL20RA Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71968	IL-20R alpha Protein, Human (HEK 293, His)	Q9UHF4 (V30-K250)	≥95%
HY-P72562	IL-20R alpha Protein, Human (221a.a, HEK293, His)	Q9UHF4 (V30-K250)	≥95%
HY-P77419	IL-20R alpha Protein, Human (HEK293, Fc)	Q9UHF4 (M1-K250)	≥95%
HY-P77420	IL-20R alpha Protein, Human (250a.a, HEK293, His)	Q9UHF4 (M1-K250)	≥95%

Related Diseases

Diseases

Alias

Psoriasis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06732	IL20RA Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	IL20RA	VGNC	VGNC:67772
Rattus norvegicus	IL20RA	RGD	RGD:1307335
Bos taurus	IL20RA	VGNC	VGNC:30139
Macaca mulatta	IL20RA	VGNC	VGNC:73724
Canis familiaris	IL20RA	VGNC	VGNC:41965
Mus musculus	IL20RA	MGD	MGI:3605069

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