CLDN22 - claudin 22 Gene

Also Known as CLDN21

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 53842

Summary

This gene encodes a member of the Claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand. [provided by RefSeq, Aug 2010]

CLDN22 Products (1)

mRNA Protein Name
NM_001111319.3 NP_001104789.1 claudin-22

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLDN22 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
CLDN22 Q8N7P3 OPRM1 Homo sapiens P35372-10
Y2H Array
32296183
Intra
CLDN22 Q8N7P3 OPRM1 Homo sapiens P35372-10
Y2H Prey Pooling
32296183
Intra
CLDN22 Q8N7P3 CLEC4C Homo sapiens Q8WTT0
Y2H Array
32296183
Intra
CLDN22 Q8N7P3 CLEC4C Homo sapiens Q8WTT0
Y2H Prey Pooling
32296183
Intra
CLDN22 Q8N7P3 CLEC4C Homo sapiens Q8WTT0
Validated Y2H
32296183
Intra
CLDN22 Q8N7P3 TREX1 Homo sapiens Q9NSU2-1
Validated Y2H
32296183
Intra
CLDN22 Q8N7P3 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
Intra
CLDN22 Q8N7P3 LHFPL5 Homo sapiens Q8TAF8
Validated Y2H
32296183
Intra
CLDN22 Q8N7P3 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
Intra
CLDN22 Q8N7P3 CXCR2 Homo sapiens P25025
Y2H Array
32296183
Intra
CLDN22 Q8N7P3 CXCR2 Homo sapiens P25025
Y2H Prey Pooling
32296183
Intra
CLDN22 Q8N7P3 SPG21 Homo sapiens Q9NZD8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS02770 CLDN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown