Rassf5 - Ras association (RalGDS/AF-6) domain family member 5 Gene

Also Known as Rapl; Maxp1; Nore1; Nore1A; Nore1B; 1300019G20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54354

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within negative regulation of cell population proliferation; positive regulation of protein ubiquitination; and regulation of protein localization to nucleus. Located in nucleus. Is expressed in heart and thymus primordium. Used to study systemic lupus erythematosus. Orthologous to human RASSF5 (Ras association domain family member 5). [provided by Alliance of Genome Resources, Apr 2022]

Rassf5 Products (3)

mRNA Protein Name
NM_001311094.2 NP_001298023.1 ras association domain-containing protein 5 isoform 2
NM_001313731.1 NP_001300660.1 ras association domain-containing protein 5 isoform 3
NM_018750.4 NP_061220.2 ras association domain-containing protein 5 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9488663 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of lymphocyte proliferation IMP
IMP: Inferred from mutant phenotype
21194982 MGI
acts upstream of or within negative regulation of lymphocyte proliferation IMP
IMP: Inferred from mutant phenotype
21194982 MGI
acts upstream of or within positive regulation of protein ubiquitination IMP
IMP: Inferred from mutant phenotype
22173032 MGI
acts upstream of or within regulation of protein localization to nucleus IMP
IMP: Inferred from mutant phenotype
21194982 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
22173032 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras association domain-containing protein 5

  • Rap1-binding protein

  • new ras effector 1

  • novel ras effector 1

  • regulator for cell adhesion and polarization enriched in lymphoid tissues

Rassf5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Rassf5 Q5EBH1 Stk4 Mus musculus Q9JI11
Anti Bait CoIP
16892067
Cross
Rassf5 Q5EBH1 HRAS Homo sapiens P01112
NMR
16698549
Cross
Rassf5 Q5EBH1 HRAS Homo sapiens P01112
Fluorescence
18596699
Cross
Rassf5 Q5EBH1 HRAS Homo sapiens P01112
ITC
16698549
Cross
Rassf5 Q5EBH1 HRAS Homo sapiens P01112
X-Ray Diffraction
18596699
Intra
Rassf5 Q5EBH1 Hras Mus musculus Q61411
Pull Down
9488663
Cross
Rassf5 Q5EBH1 RAP1A Homo sapiens P62834
ITC
16698549
Cross
Rassf5 Q5EBH1 RAP1A Homo sapiens P62834
Anti Tag CoIP
12845325
Intra
Rassf5 Q5EBH1 Mdm2 Mus musculus P23804
Y2H
22173032
Intra
Rassf5 Q5EBH1 Hipk1 Mus musculus O88904
Y2H
22173032
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11703 RASSF3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11705 RASSF5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21184 Rassf5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27700 Rassf5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rassf5 NCBI NCBI:83593