2. Gene
  3. ARHGAP17 - Rho GTPase activating protein 17 Gene

ARHGAP17 - Rho GTPase activating protein 17 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PP367; RICH1; WBP15; MST066; MST110; NADRIN; PP4534; RICH-1; MSTP038; MSTP066; MSTP110

Gene ID: 55114 | Gene type: protein coding

About ARHGAP17

Cytogenetic location: 16p12.1 Genomic coordinates (GRCh38): 16:24,919,389-25,015,369 (from NCBI)

This gene has 20 transcripts (splice variants), 1 gene allele, 290 orthologues and 2 paralogues. Ubiquitous expression in spleen (RPKM 24.3), lymph node (RPKM 19.6) and 25 other tissues.

Summary

RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA (MIM 165390), RAC1 (MIM 602048), and CDC42 (MIM 116952).[supplied by OMIM, Apr 2004]

ARHGAP17 Products(2)

mRNA Protein Name
NM_001006634.3 NP_001006635.1 rho GTPase-activating protein 17 isoform 1
NM_018054.6 NP_060524.4 rho GTPase-activating protein 17 isoform 2

ARHGAP17 Protein Structure

BAR

BAR: BAR domain (1 - 238)

RhoGAP

RhoGAP: RhoGAP domain (268 - 412)

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  • 881 a.a.
Protein Preferred Names Protein Names

rho GTPase-activating protein 17

RhoGAP interacting with CIP4 homologs 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00917 ARHGAP17 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ARHGAP17 RGD RGD:628767
Canis familiaris ARHGAP17 VGNC VGNC:38048
Macaca mulatta ARHGAP17 VGNC VGNC:99484
Mus musculus ARHGAP17 MGD MGI:1917747
Felis catus ARHGAP17 VGNC VGNC:59877
Bos taurus ARHGAP17 VGNC VGNC:26077