2. Gene
  3. MRGBP - MRG domain binding protein Gene

MRGBP - MRG domain binding protein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as Eaf7; URCC4; MRG15BP; C20orf20

Gene ID: 55257 | Gene type: protein coding

About MRGBP

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:62,796,473-62,801,729 (from NCBI)

This gene has 1 transcript (splice variant) and 195 orthologues. Broad expression in testis (RPKM 23.2), ovary (RPKM 4.6) and 24 other tissues.

Summary

Predicted to be involved in histone acetylation and regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MRGBP Products(1)

mRNA Protein Name
NM_018270.6 NP_060740.1 MRG/MORF4L-binding protein

MRGBP Protein Structure

Eaf7

Eaf7: Chromatin modification-related protein EAF7 (34 - 113)

  • 0
  • 100
  • 204 a.a.
Protein Preferred Names Protein Names

MRG/MORF4L-binding protein

MRG-binding protein

Related Diseases

Diseases Alias
Intellectual Developmental Disorder, Autosomal Dominant 5

MRD5

Autosomal Dominant Non-Syndromic Intellectual Disability 5

Intellectual Disability, Autosomal Dominant 5

Mental Retardation, Autosomal Dominant 5

Autosomal Dominant Intellectual Developmental Disorder 5

Syngap1-Related Non-Syndromic Intellectual Disability

Autosomal Dominant Intellectual Disability 5

Syngap1 Syndrome

Syngap1-Related Nsid

Syngap1 Gene Mutation Linked To Intellectual Disability, Schizophrenia And Autism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08646 MRGBP Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MRGBP MGD MGI:1920497
Canis familiaris MRGBP VGNC VGNC:54654
Felis catus MRGBP VGNC VGNC:81122
Rattus norvegicus MRGBP RGD RGD:1308612
Macaca mulatta MRGBP VGNC VGNC:95363
Bos taurus MRGBP VGNC VGNC:31602