ANP32E - acidic nuclear phosphoprotein 32 family member E Gene

Also Known as LANPL; LANP-L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 81611

About ANP32E

Cytogenetic location: 1q21.2 Genomic coordinates (GRCh38): 1:150,218,417-150,236,112 (from NCBI)

This gene has 10 transcripts (splice variants), 284 orthologues and 3 paralogues. Ubiquitous expression in lymph node (RPKM 31.5), bone marrow (RPKM 21.4) and 24 other tissues.

Summary

Enables histone binding activity. Involved in histone exchange. Located in nucleus. Part of Swr1 complex. [provided by Alliance of Genome Resources, Apr 2022]

ANP32E Products (5)

mRNA Protein Name
NM_001136478.4 NP_001129950.1 acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 2
NM_001136479.3 NP_001129951.1 acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 3
NM_001280559.2 NP_001267488.1 acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 4
NM_001280560.2 NP_001267489.1 acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 5
NM_030920.5 NP_112182.1 acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables histone binding IDA
IDA: Inferred from direct assay
24463511 GOA
enables histone chaperone activity IDA
IDA: Inferred from direct assay
24463511 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
24463511 GOA
enables protein folding chaperone EXP
EXP: Inferred from Experiment
24613878 GOA
Cellular Component GO Annotation Evidence References Source
part of Swr1 complex IDA
IDA: Inferred from direct assay
24463511 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ANP32E Protein Structure

LRR_4

LRR_4: Leucine Rich repeats (2 copies) (88 - 130)

  • 0
  • 100
  • 200
  • 268 a.a.
Protein Preferred Names Protein Names

acidic leucine-rich nuclear phosphoprotein 32 family member E

  • LANP-like protein

ANP32E Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ANP32E Q9BTT0 MRGBP Homo sapiens Q9NV56
Cosedimentation
24463511
Intra
ANP32E Q9BTT0 MRGBP Homo sapiens Q9NV56
TAP
24463511
Cross: Cross-species interaction Intra: Intraspecies interaction

ANP32E Antibodies

Cat. No. Product Name Application Reactivity
HY-P811344 ANP32E Antibody WB, ICC/IF Human, Mouse

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00753 ANP32E Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ANP32E VGNC VGNC:59836
Mus musculus ANP32E MGD MGI:1913721
Rattus norvegicus ANP32E RGD RGD:1310611
Canis familiaris ANP32E VGNC VGNC:37934
Macaca mulatta ANP32E VGNC VGNC:97733
Bos taurus ANP32E VGNC VGNC:25959
Others ANP32E NCBI