2. Gene
  3. CDC37L1 - cell division cycle 37 like 1, HSP90 cochaperone Gene

CDC37L1 - cell division cycle 37 like 1, HSP90 cochaperone Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HARC; CDC37B

Gene ID: 55664 | Gene type: protein coding

About CDC37L1

Cytogenetic location: 9p24.1 Genomic coordinates (GRCh38): 9:4,679,569-4,708,399 (from NCBI)

This gene has 3 transcripts (splice variants), 209 orthologues and 1 paralogue. Ubiquitous expression in liver (RPKM 13.5), heart (RPKM 8.3) and 25 other tissues.

Summary

CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 [PubMed 11413142]).[supplied by OMIM, Mar 2008]

CDC37L1 Products(1)

mRNA Protein Name
NM_017913.4 NP_060383.2 hsp90 co-chaperone Cdc37-like 1

CDC37L1 Protein Structure

CDC37_M

CDC37_M: Cdc37 Hsp90 binding domain (132 - 282)

  • 0
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  • 200
  • 300
  • 337 a.a.
Protein Preferred Names Protein Names

hsp90 co-chaperone Cdc37-like 1

CDC37 cell division cycle 37 homolog-like 1

Related Diseases

Diseases Alias
Delusional Disorder

Persistent Delusional Disorders

Delusional Perception

Induced Delusional Disorder
Ulceroglandular Tularemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111414 Hsp90-Cdc37-IN-1 Inhibitor 99.66% Unkown
HY-RS02298 CDC37L1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CDC37L1 VGNC VGNC:27067
Macaca mulatta CDC37L1 VGNC VGNC:70790
Rattus norvegicus CDC37L1 RGD RGD:1309295
Canis familiaris CDC37L1 VGNC VGNC:38995
Mus musculus CDC37L1 MGD MGI:1914322
Felis catus CDC37L1 VGNC VGNC:60655