2. Gene
  3. EMC3 - ER membrane protein complex subunit 3 Gene

EMC3 - ER membrane protein complex subunit 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as POB; TMEM111

Gene ID: 55831 | Gene type: protein coding

About EMC3

This gene has 8 transcripts (splice variants) and 211 orthologues. Ubiquitous expression in fat (RPKM 29.9), testis (RPKM 23.1) and 25 other tissues.

Summary

Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Is integral component of endoplasmic reticulum membrane. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2022]

EMC3 Products(2)

mRNA Protein Name
NM_001394674.1 NP_001381603.1 ER membrane protein complex subunit 3
NM_018447.4 NP_060917.1 ER membrane protein complex subunit 3

EMC3 Protein Structure

DUF106

DUF106: Integral membrane protein DUF106 (5 - 191)

  • 0
  • 100
  • 200
  • 261 a.a.
Protein Preferred Names Protein Names

ER membrane protein complex subunit 3

30 kDa protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04338 EMC3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus EMC3 VGNC VGNC:61834
Mus musculus EMC3 MGD MGI:1913337
Bos taurus EMC3 VGNC VGNC:28464
Canis familiaris EMC3 VGNC VGNC:40333
Macaca mulatta EMC3 VGNC VGNC:72091
Rattus norvegicus EMC3 RGD RGD:1311566