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56124

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34

Inhibitors & Agonists

4

Isotope-Labeled Compounds

5

Antibodies

20

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0211
    Riluzole
    Maximum Cited Publications
    14 Publications Verification

    PK 26124

    Sodium Channel GABA Receptor Neurological Disease Cancer
    Riluzole is an anticonvulsant agent and belongs to the family of use-dependent Na + channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
    Riluzole
  • HY-B0211A
    Riluzole hydrochloride
    Maximum Cited Publications
    14 Publications Verification

    PK 26124 hydrochloride

    Sodium Channel GABA Receptor Neurological Disease Cancer
    Riluzole hydrochloride is an anticonvulsant agent and belongs to the family of use-dependent Na + channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
    Riluzole hydrochloride
  • HY-15430A
    Encenicline hydrochloride
    5 Publications Verification

    EVP-6124 hydrochloride

    nAChR Neurological Disease
    Encenicline hydrochloride (EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
    Encenicline hydrochloride
  • HY-Y1075S1

    Aminocyclopropane-d5; NSC 56127-d5

    Isotope-Labeled Compounds Others
    Cyclopropylamine-d5 is the deuterium labeled Cyclopropanamine .
    Cyclopropylamine-d5
  • HY-164927

    Influenza Virus Infection Inflammation/Immunology
    AV5124, a prodrug of AV5116, is an orally active influenza virus cap-dependent endonuclease (CEN) endonuclease inhibitor .
    AV5124
  • HY-B0211R

    PK 26124 (Standard)

    Reference Standards Sodium Channel GABA Receptor Neurological Disease Cancer
    Riluzole (Standard) is the analytical standard of Riluzole. This product is intended for research and analytical applications. Riluzole is an anticonvulsant agent and belongs to the family of use-dependent Na + channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
    Riluzole (Standard)
  • HY-15430

    EVP-6124

    nAChR Neurological Disease
    Encenicline (EVP-6124) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
    Encenicline
  • HY-18952A

    FLT3 Apoptosis Cancer
    (Z)-SU5614 is a potent FLT3 inhibitor and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3 .
    (Z)-SU5614
  • HY-B0211S1

    PK 26124-13C6

    Isotope-Labeled Compounds Sodium Channel GABA Receptor Neurological Disease Cancer
    Riluzole- 13C6 (PK 26124- 13C6) is 13C labeled Riluzole. Riluzole is an anticonvulsant agent and belongs to the family of use-dependent Na + channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
    Riluzole-13C6
  • HY-131508

    Parasite Infection
    M&B 5124 is a potent inhibitor of Schistosoma mansoni in mice .
    M&B 5124
  • HY-R01868A

    MicroRNA Cancer
    hsa-miR-6124 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6124 agomir
    hsa-miR-6124 agomir
  • HY-R01868

    MicroRNA Cancer
    hsa-miR-6124 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-6124 mimic
    hsa-miR-6124 mimic
  • HY-RI03268A

    MicroRNA Cancer
    mmu-miR-5124a antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-5124a antagomir
    mmu-miR-5124a antagomir
  • HY-R03268A

    MicroRNA Cancer
    mmu-miR-5124a agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-5124a agomir
    mmu-miR-5124a agomir
  • HY-R03268

    MicroRNA Cancer
    mmu-miR-5124a mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-5124a mimic
    mmu-miR-5124a mimic
  • HY-R03269

    MicroRNA Cancer
    mmu-miR-5124b mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-5124b mimic
    mmu-miR-5124b mimic
  • HY-R03316

    MicroRNA Cancer
    mmu-miR-5624-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-5624-3p mimic
    mmu-miR-5624-3p mimic
  • HY-RI03316A

    MicroRNA Cancer
    mmu-miR-5624-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-5624-3p antagomir
    mmu-miR-5624-3p antagomir
  • HY-R03317

    MicroRNA Cancer
    mmu-miR-5624-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-5624-5p mimic
    mmu-miR-5624-5p mimic
  • HY-Y1075S2

    Aminocyclopropane-d4; NSC 56127-d4

    Isotope-Labeled Compounds Others
    Cyclopropyl-2,2,3,3-amine-d4 is the deuterium labeled Cyclopropanamine .
    Cyclopropyl-2,2,3,3-amine-d4
  • HY-B0211S

    PK 26124-13C,15N2

    GABA Receptor Sodium Channel Neurological Disease
    Riluzole- 13C, 15N2 is the 13C and 15N labeled Riluzole . Riluzole is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM .
    Riluzole-13C,15N2
  • HY-B0211AR

    PK 26124 hydrochloride (Standard)

    Sodium Channel GABA Receptor Reference Standards Neurological Disease Cancer
    Riluzole hydrochloride (Standard) is the analytical standard of Riluzole hydrochloride. This product is intended for research and analytical applications. Riluzole hydrochloride is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
    Riluzole hydrochloride (Standard)
  • HY-183626

    PAI-1 Ser/Thr Protease Furin MMP Notch Apoptosis Inflammation/Immunology Cancer
    TM5614 sodium is an orally active and specific PAI-1 inhibitor with an IC50 of <6.95 μM. TM5614 sodium blocks the interaction between PAI-1 and serine proteases or LRP-1, and enhances plasmin generation. TM5614 sodium restores macrophage efferocytosis and promotes macrophage polarization. TM5614 sodium alleviates PAI-1-mediated inhibition of Furin, promotes MT1-MMP maturation, activates the NOTCH1 signaling pathway, inhibits proliferation and induces apoptosis. TM5614 sodium promotes skeletal muscle regeneration and alleviates inflammation in a mouse model of skeletal muscle injury. TM5614 sodium can be used in research on skeletal muscle injury-induced inflammation and chronic myeloid leukemia .
    TM5614 sodium
  • HY-RI01868A

    MicroRNA Cancer
    hsa-miR-6124 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6124 antagomir
    hsa-miR-6124 antagomir
  • HY-RI01868

    MicroRNA Cancer
    hsa-miR-6124 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-6124 inhibitor
    hsa-miR-6124 inhibitor
  • HY-RI03269A

    MicroRNA Cancer
    mmu-miR-5124b antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-5124b antagomir
    mmu-miR-5124b antagomir
  • HY-RI03269

    MicroRNA Cancer
    mmu-miR-5124b inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-5124b inhibitor
    mmu-miR-5124b inhibitor
  • HY-R03269A

    MicroRNA Cancer
    mmu-miR-5124b agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-5124b agomir
    mmu-miR-5124b agomir
  • HY-RI03268

    MicroRNA Cancer
    mmu-miR-5124a inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-5124a inhibitor
    mmu-miR-5124a inhibitor
  • HY-RI03317

    MicroRNA Cancer
    mmu-miR-5624-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-5624-5p inhibitor
    mmu-miR-5624-5p inhibitor
  • HY-RI03316

    MicroRNA Cancer
    mmu-miR-5624-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-5624-3p inhibitor
    mmu-miR-5624-3p inhibitor
  • HY-R03316A

    MicroRNA Cancer
    mmu-miR-5624-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-5624-3p agomir
    mmu-miR-5624-3p agomir
  • HY-RI03317A

    MicroRNA Cancer
    mmu-miR-5624-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-5624-5p antagomir
    mmu-miR-5624-5p antagomir
  • HY-R03317A

    MicroRNA Cancer
    mmu-miR-5624-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-5624-5p agomir
    mmu-miR-5624-5p agomir

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