NSMCE3 - NSE3 homolog, SMC5-SMC6 complex component Gene

Also Known as HCA4; LICS; NSE3; NDNL2; MAGEG1; MAGEL3

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 56160

Summary

The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. [provided by RefSeq, May 2011]

NSMCE3 Products (1)

mRNA Protein Name
NM_138704.4 NP_619649.1 non-structural maintenance of chromosomes element 3 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18086888 GOA
enables protein dimerization activity IDA
IDA: Inferred from direct assay
27427983 GOA
Biological Process GO Annotation Evidence References Source
involved in DNA repair IMP
IMP: Inferred from mutant phenotype
27427983 GOA
involved in cellular response to UV IMP
IMP: Inferred from mutant phenotype
27427983 GOA
involved in cellular response to hydroxyurea IMP
IMP: Inferred from mutant phenotype
27427983 GOA
involved in cellular response to radiation IMP
IMP: Inferred from mutant phenotype
27427983 GOA
involved in positive regulation of protein ubiquitination IDA
IDA: Inferred from direct assay
20864041 GOA
Cellular Component GO Annotation Evidence References Source
part of Smc5-Smc6 complex IDA
IDA: Inferred from direct assay
18086888 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

non-structural maintenance of chromosomes element 3 homolog

  • MAGE-G1 antigen

  • hepatocellular carcinoma-associated protein 4

  • hepatocellular carcinoma-associated protein HCA4

  • melanoma antigen, family G, 1

  • melanoma-associated antigen G1

  • necdin-like 2, SMC5-SMC6 complex component

  • necdin-like gene 2

  • necdin-like pr

NSMCE3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NSMCE3 Q96MG7 NSMCE1 Homo sapiens Q8WV22
TAP
20864041
Intra
NSMCE3 Q96MG7 NSMCE1 Homo sapiens Q8WV22
X-Ray Diffraction
20864041
Intra
NSMCE3 Q96MG7 NSMCE1 Homo sapiens Q8WV22
Anti Tag CoIP
18086888
Intra
NSMCE3 Q96MG7 NSMCE1 Homo sapiens Q8WV22
Anti Tag CoIP
20864041
Intra
NSMCE3 Q96MG7 NSMCE1 Homo sapiens Q8WV22
GMS
27427983
Intra
NSMCE3 Q96MG7 NSMCE1 Homo sapiens Q8WV22
Anti Tag CoIP
21364888
Intra
NSMCE3 Q96MG7 NSMCE1 Homo sapiens Q8WV22
Y2H
27427983
Intra
NSMCE3 Q96MG7 NSMCE1 Homo sapiens Q8WV22
GMS
20864041
Intra
NSMCE3 Q96MG7 NSMCE1 Homo sapiens Q8WV22
Anti Tag CoIP
27427983
Intra
NSMCE3 Q96MG7 NSMCE1 Homo sapiens Q8WV22
Pull Down
20864041
Intra
NSMCE3 Q96MG7 NSMCE4A Homo sapiens Q9NXX6
Anti Tag CoIP
33961781
Intra
NSMCE3 Q96MG7 NSMCE4A Homo sapiens Q9NXX6
Pull Down
20864041
Intra
NSMCE3 Q96MG7 SMC6 Homo sapiens Q96SB8
Anti Tag CoIP
18086888
Intra
NSMCE3 Q96MG7 SMC6 Homo sapiens Q96SB8
Anti Tag CoIP
33961781
Intra
NSMCE3 Q96MG7 PJA1 Homo sapiens Q8NG27
TAP
20864041
Intra
NSMCE3 Q96MG7 PJA1 Homo sapiens Q8NG27
Pull Down
20864041
Intra
NSMCE3 Q96MG7 EID3 Homo sapiens Q8N140
Y2H
21364888
Intra
NSMCE3 Q96MG7 EID3 Homo sapiens Q8N140
Anti Tag CoIP
21364888
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09597 NSMCE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09598 NSMCE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown