Med20 - mediator complex subunit 20 Gene

Also Known as Trfp; 1110011O05Rik; 2410115I17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56771

Summary

Predicted to enable transcription coactivator activity. Predicted to contribute to ubiquitin protein Ligase activity. Acts upstream of or within skeletal muscle cell differentiation. Part of mediator complex. Is expressed in several structures, including early conceptus; eye; limb mesenchyme; and oocyte. Orthologous to human MED20 (mediator complex subunit 20). [provided by Alliance of Genome Resources, Apr 2022]

Med20 Products (3)

mRNA Protein Name
NM_001364926.1 NP_001351855.1 mediator of RNA polymerase II transcription subunit 20 isoform 2
NM_001364927.1 NP_001351856.1 mediator of RNA polymerase II transcription subunit 20 isoform 3
NM_020048.4 NP_064432.1 mediator of RNA polymerase II transcription subunit 20 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12584197 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
22147266 MGI
Cellular Component GO Annotation Evidence References Source
part of mediator complex IDA
IDA: Inferred from direct assay
15340084 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 20

  • Trf (TATA binding protein-related factor)-proximal protein homolog

  • ubiquitin specific protease 49

Med20 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Med20 Q9R0X0 Med30 Mus musculus Q9CQI9
Anti Tag CoIP
24882805
Cross
Med20 Q9R0X0 MED27 Homo sapiens Q6P2C8
Anti Tag CoIP
24882805
Cross
Med20 Q9R0X0 MED18 Homo sapiens Q9BUE0
Anti Tag CoIP
24882805
Cross
Med20 Q9R0X0 MED18 Homo sapiens Q9BUE0
Anti Tag CoIP
12584197
Cross
Med20 Q9R0X0 MED18 Homo sapiens Q9BUE0
Biochemical
12584197
Cross
Med20 Q9R0X0 MED18 Homo sapiens Q9BUE0
Pull Down
12584197
Cross
Med20 Q9R0X0 MED29 Homo sapiens Q9NX70
Anti Tag CoIP
24882805
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08291 MED20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Med20 NCBI NCBI:9477