MED29 - mediator complex subunit 29 Gene

Homo sapiens

Also known as IXL; MED2

Gene ID: 55588 | Gene type: protein coding

About MED29

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:39,391,378-39,400,641 (from NCBI)

This gene has 6 transcripts (splice variants) and 88 orthologues. Ubiquitous expression in brain (RPKM 2.7), thyroid (RPKM 2.6) and 25 other tissues.

Summary

MED29 is a subunit of the Mediator complex, a multiprotein coactivator of RNA transcription that interacts with DNA-bound transcriptional activators, RNA polymerase II (see MIM 180660), and general initiation factors (Sato et al., 2003 [PubMed 14576168]).[supplied by OMIM, Aug 2009]

MED29 Products(2)

mRNA	Protein	Name
NM_001317770.3	NP_001304699.2	mediator of RNA polymerase II transcription subunit 29 isoform 2
NM_017592.4	NP_060062.2	mediator of RNA polymerase II transcription subunit 29 isoform 1

MED29 Protein Structure

Med29

0
100
200 a.a.

Protein Preferred Names

Protein Names

mediator of RNA polymerase II transcription subunit 29

intersex-like protein

Related Diseases

Diseases

Alias

Fleck Retina, Familial Benign

FRFB	Familial Benign Flecked Retina
Familial Benign Fleck Retina

Fetishism

Fetishism, Psychiatric

Bubonic Plague

Black Death	Plague, Bubonic
Plague, Septicemic	Pestis Bubonica

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08300	MED29 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MED29	MGD	MGI:1914474
Canis familiaris	MED29	VGNC	VGNC:43136
Rattus norvegicus	MED29	RGD	RGD:1311009
Macaca mulatta	MED29	VGNC	VGNC:74557
Bos taurus	MED29	VGNC	VGNC:31365

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