Med30 - mediator complex subunit 30 Gene

Also Known as TRAP25; Thrap6; 1810038N03Rik; 2510044J04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69790

Summary

Predicted to enable Thyroid Hormone Receptor binding activity and transcription coactivator activity. Predicted to contribute to ubiquitin protein Ligase activity. Acts upstream of or within stem cell population maintenance. Part of mediator complex. Is expressed in several structures, including branchial arch; central nervous system; limb; limb bud; and trunk somite. Orthologous to human MED30 (mediator complex subunit 30). [provided by Alliance of Genome Resources, Apr 2022]

Med30 Products (1)

mRNA Protein Name
NM_027212.2 NP_081488.1 mediator of RNA polymerase II transcription subunit 30

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11591653 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within somatic stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
20720539 MGI
Cellular Component GO Annotation Evidence References Source
part of mediator complex IDA
IDA: Inferred from direct assay
15340084 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 30

  • TRAP/Mediator complex component TRAP25

  • thyroid hormone receptor associated protein 6

  • thyroid hormone receptor-associated protein complex 25 kDa component

Med30 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Med30 Q9CQI9 MED22 Homo sapiens Q15528
Pull Down
12584197
Cross
Med30 Q9CQI9 MED22 Homo sapiens Q15528
Anti Tag CoIP
24882805
Cross
Med30 Q9CQI9 MED22 Homo sapiens Q15528
Anti Tag CoIP
12584197
Cross
Med30 Q9CQI9 MED28 Homo sapiens Q9H204
Anti Tag CoIP
24882805
Intra
Med30 Q9CQI9 Med8 Mus musculus Q9D7W5
Anti Tag CoIP
24882805
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08301 MED30 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Med30 NCBI NCBI:90390