Gpr17 - G protein-coupled receptor 17 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 574402

Summary

Predicted to enable G protein-coupled receptor activity and receptor serine/threonine kinase binding activity. Acts upstream of or within negative regulation of inflammatory response to antigenic stimulus. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in central nervous system; gut; and male reproductive gland or organ. Orthologous to human GPR17 (G protein-coupled receptor 17). [provided by Alliance of Genome Resources, Apr 2022]

Gpr17 Products (1)

mRNA Protein Name
NM_001025381.2 NP_001020552.1 uracil nucleotide/cysteinyl leukotriene receptor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19561298 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of inflammatory response to antigenic stimulus IGI
IGI: Inferred from genetic interaction
20574000 MGI
acts upstream of or within negative regulation of inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
20574000 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

uracil nucleotide/cysteinyl leukotriene receptor

  • UDP/CysLT receptor

Gpr17 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Gpr17 Q6NS65 Cysltr1 Mus musculus Q99JA4
Anti Tag CoIP
19561298
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-19638A Cangrelor tetrasodium Antagonist 99.96% Unkown
HY-19638 Cangrelor Antagonist / Unkown

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-146486 P2Y2R/GPR17 antagonist 1 Inhibitor 98.09% Unkown
HY-111323 ASN06917370 99.23% Unkown
HY-128111 ASN02563583 Activator 99.21% Unkown
HY-113667 ASN04885796 Activator 99.61% Unkown
HY-170589 GPR17 antagonist 1 Antagonist 98.95% Unkown
HY-128128 ASN04421891 Modulator 99.00% Unkown
HY-107752A 2-(Phenylethynyl)-ATP ammonium / Unkown
HY-125313 PSB-1737 Agonist / Unkown
HY-159920 PSB-22269 Antagonist / Unkown
HY-164311 GPR17 modulator-1 Modulator / Unkown
HY-179606 RWT9996 / Unkown
HY-181738 GPR17 agonist 2 / Unkown
HY-182724 PSB-18422 Agonist / Unkown
HY-RS05679 GPR17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17462 Gpr17 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23920 Gpr17 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr17 NCBI NCBI:2840