2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. ROR
  4. ASN06917370

ASN06917370 is a former orphan receptor GPR17 ligand for the study of neurodegenerative diseases. ASN06917370 has an EC50 of 268 pM in [35S]GTPyS experiments.

For research use only. We do not sell to patients.

ASN06917370 Chemical Structure

ASN06917370 Chemical Structure

CAS No. : 837404-68-9

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5 mg USD 326 In-stock
10 mg USD 490 In-stock
25 mg USD 980 In-stock
50 mg USD 1470 In-stock
100 mg USD 2205 In-stock
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Based on 1 publication(s) in Google Scholar

ASN06917370 Related Antibodies

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Description

ASN06917370 is a former orphan receptor GPR17 ligand for the study of neurodegenerative diseases. ASN06917370 has an EC50 of 268 pM in [35S]GTPyS experiments[1].

IC50 & Target

GPR17[1]
Molecular Weight

531.92

Formula

C24H21ClF3N7O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CCC(C2=NC3=C(N=NN3CC4=CC=CC=C4Cl)C(N2)=O)CC1)NC5=CC=C(C(F)(F)F)C=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 2 mg/mL (3.76 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8800 mL 9.3999 mL 18.7998 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8800 mL 9.3999 mL 18.7998 mL 46.9996 mL
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ASN06917370 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ASN06917370837404-68-9ASN 06917370ASN-06917370RORRAR-related orphan receptorNeurodegenerative diseasesreceptor activating properties.Inhibitorinhibitorinhibit

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HY-111323
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