2. Gene
  3. CIP2A - cellular inhibitor of PP2A Gene

CIP2A - cellular inhibitor of PP2A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as p90; NOCIVA; KIAA1524

Gene ID: 57650 | Gene type: protein coding

About CIP2A

Cytogenetic location: 3q13.13 Genomic coordinates (GRCh38): 3:108,549,864-108,589,438 (from NCBI)

This gene has 7 transcripts (splice variants), 200 orthologues and 2 paralogues. Broad expression in testis (RPKM 2.5), lymph node (RPKM 2.3) and 22 other tissues.

Summary

Enables protein homodimerization activity. Predicted to act upstream of or within positive regulation of neural precursor cell proliferation and spermatogenesis. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CIP2A Products(1)

mRNA Protein Name
NM_020890.3 NP_065941.2 protein CIP2A
Protein Preferred Names Protein Names

protein CIP2A

cancerous inhibitor of PP2A

Related Diseases

Diseases Alias
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-135699 TD52 ≥95.0% Unkown
HY-N4317 Ethoxysanguinarine Inducer 99.73% Unkown
HY-135699A TD52 dihydrochloride 99.90% Unkown
HY-139296 PP2A Cancerous-IN-1 Inhibitor / Unkown
HY-RS02718 CIP2A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CIP2A RGD RGD:1310335
Canis familiaris CIP2A VGNC VGNC:39277
Felis catus CIP2A VGNC VGNC:60906
Bos taurus CIP2A VGNC VGNC:27369
Macaca mulatta CIP2A VGNC VGNC:71371
Mus musculus CIP2A MGD MGI:2146335