2. Gene
  3. IL22RA1 - interleukin 22 receptor subunit alpha 1 Gene

IL22RA1 - interleukin 22 receptor subunit alpha 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as IL22R; CRF2-9; IL22R1

Gene ID: 58985 | Gene type: protein coding

About IL22RA1

Cytogenetic location: 1p36.11 Genomic coordinates (GRCh38): 1:24,119,771-24,143,140 (from NCBI)

This gene has 1 transcript (splice variant), 231 orthologues and 11 paralogues. Biased expression in pancreas (RPKM 15.5), skin (RPKM 14.3) and 9 other tissues.

Summary

The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]

IL22RA1 Products(1)

mRNA Protein Name
NM_021258.4 NP_067081.2 interleukin-22 receptor subunit alpha-1 precursor

IL22RA1 Protein Structure

Tissue_fac

Tissue_fac: Tissue factor (15 - 106)

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  • 574 a.a.
Protein Preferred Names Protein Names

interleukin-22 receptor subunit alpha-1

IL-22 receptor subunit alpha-1

Recombinant IL22RA1 Proteins

Cat. No. Product Name Accession Purity
HY-P77967 IL-22R alpha 1 Protein, Human (HEK293, Fc) Q8N6P7 (H16-T228) ≥95%

Related Diseases

Diseases Alias
Spondyloarthropathy

Spondylarthropathies

Spondarthropathy

Spondylarthrosis

Spondyloarthropathy, Susceptibility To

Spondylarthritis
Erythematosquamous Dermatosis

Other Erythematosquamous Dermatosis
Rheumatoid Arthritis

RA

Arthritis, Rheumatoid

Rheumatoid Arthritis, Susceptibility To

Arthritis Or Polyarthritis, Rheumatic

Atrophic Arthritis

Rheumatism Arthritis

Rheumatoid Polyarthritis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06737 IL22RA1 Human Pre-designed siRNA Set A / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990016 Temtokibart Inhibitor 99.23% Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus IL22RA1 VGNC VGNC:30144
Canis familiaris IL22RA1 VGNC VGNC:41970
Macaca mulatta IL22RA1 VGNC VGNC:106386
Felis catus IL22RA1 VGNC VGNC:62905
Rattus norvegicus IL22RA1 RGD RGD:1559655
Mus musculus IL22RA1 MGD MGI:2663588