SPCS3 - signal peptidase complex subunit 3 Gene

Homo sapiens

Also known as SPC3; SPC22; SPC23; PRO3567; YLR066W; SPC22/23

Gene ID: 60559 | Gene type: protein coding

About SPCS3

Cytogenetic location: 4q34.2 Genomic coordinates (GRCh38): 4:176,319,966-176,332,245 (from NCBI)

This gene has 4 transcripts (splice variants) and 215 orthologues. Ubiquitous expression in thyroid (RPKM 45.3), appendix (RPKM 34.4) and 25 other tissues.

Summary

Predicted to enable peptidase activity. Involved in proteolysis and viral protein processing. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

SPCS3 Products(1)

mRNA	Protein	Name
NM_021928.4	NP_068747.1	signal peptidase complex subunit 3

SPCS3 Protein Structure

SPC22

0
100
180 a.a.

Protein Preferred Names

Protein Names

signal peptidase complex subunit 3

SPase 22 kDa subunit

Related Diseases

Diseases

Alias

Omsk Hemorrhagic Fever

Ohf	Hemorrhagic Fever, Omsk
Ohf - [Omsk Haemorrhagic Fever]	Spring-Fall Haemorrhagic Fever

Tick Infestation

Tick Infestations

Mixed Ductal-Endocrine Carcinoma

Yellow Fever

Urban Yellow Fever	Jungle Yellow Fever
Sylvatic Yellow Fever	Yf
Yellow Fever, Sylvan	Bronze John
Yellow Jack	Yf- [Yellow Fever]
Febris Flava

Parasitic Ectoparasitic Infectious Disease

Ectoparasitic Infestations

Ectoparasitism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13651	SPCS3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SPCS3	VGNC	VGNC:82299
Felis catus	SPCS3	VGNC	VGNC:107468
Rattus norvegicus	SPCS3	RGD	RGD:1588184
Macaca mulatta	SPCS3	VGNC	VGNC:77995
Mus musculus	SPCS3	MGD	MGI:1923937
Bos taurus	SPCS3	VGNC	VGNC:58352

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