CCL24 - C-C motif chemokine ligand 24 Gene

Homo sapiens

Also known as Ckb-6; MPIF2; MPIF-2; SCYA24

Gene ID: 6369 | Gene type: protein coding

About CCL24

Cytogenetic location: 7q11.23 Genomic coordinates (GRCh38): 7:75,810,825-75,823,372 (from NCBI)

This gene has 2 transcripts (splice variants), 100 orthologues and 25 paralogues. Biased expression in small intestine (RPKM 18.6), colon (RPKM 9.1) and 8 other tissues.

Summary

This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. This protein also has antimicrobial activity, displaying an Antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. Finally, the protein is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2020]

CCL24 Products(2)

mRNA	Protein	Name
NM_001371193.1	NP_001358122.1	C-C motif chemokine 24 precursor
NM_002991.3	NP_002982.2	C-C motif chemokine 24 precursor

CCL24 Protein Structure

IL8

0
100
119 a.a.

Protein Preferred Names

Protein Names

C-C motif chemokine 24

CK-beta-6

Recombinant CCL24 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7161	CCL24/Eotaxin-2 Protein, Human	O00175 (V27-A104)	≥95%
HY-P7766	CCL24/Eotaxin-2 Protein, Human (HEK293, His)	O00175 (V27-C119)	≥95%

Related Diseases

Diseases

Alias

Vernal Keratoconjunctivitis

Vkc	Spring Catarrh
Keratoconjunctivitis Vernal	Keratoconjunctivitis, Vernal

Allergic Asthma

Atopic Asthma	Extrinsic Asthma
Extrinsic Asthma With Acute Exacerbation	Extrinsic Asthma With Status Asthmaticus
Asthma Allergic	Atopic Asthma, Susceptibility To
Ige-Mediated Allergic Asthma	Allergen-Induced Asthma
Allergic Asthma Without Stated Status Asthmaticus	Predominantly Allergic Asthma Without Stated Status Asthmaticus
Predominantly Allergic Asthma	Allergic Asthma Nos
Catarrh With Asthma	Allergic Bronchitis Nos
Extrinsic Allergic Asthma	Predominantly Allergic Asthma With Stated Status Asthmaticus

Neurosyphilis

Syphilis Of Central Nervous System	Late Syphilis Of Central Nervous System Nos
Late Syphilis Of The Central Nervous System	Gumma Of Central Nervous System
Neurosyphilis Gumma	Neurosyphilitic Gumma
Syphilis Of Central Nervous System Nos	Syphilitic Gumma Of Central Nervous System
Tertiary Central Nervous System Syphilis

Parenchymatous Neurosyphilis

Mansonelliasis

Mansonellosis	Mansonella Perstans Infections
Mansonella Infestation

Hypereosinophilic Syndrome

Eosinophilia	HES
Eosinophilic Leukocytosis	Hypereosinophilic Syndrome, Idiopathic
Idiopathic Hypereosinophilic Syndrome	Disseminated Eosinophilic Collagen Disease
Eosinophilic Disorder	Disorders With Increased Eosinophil Counts

Allergic Disease

Hypersensitivity	Allergic Hypersensitivity Disease
Allergic Condition	Allergic Reaction
Allergic Disposition

Allergic Rhinitis

Hay Fever	Allergic Rhinitis, Susceptibility To
ALRH	Atopic Rhinitis
Seasonal Allergic Rhinitis	Non-Seasonal Allergic Rhinitis
Perenial Allergic Rhinitis	Pollenosis
Rhinitis Allergic Seasonal	Rhinitis, Allergic, Perennial
Allergic Rhinitis, Cause Unspecified	Pollinosis
Pollen Allergy	Allergy Nos Due To Pollen
Summer Catarrh	Other Seasonal Allergic Rhinitis

Esophagitis

Acute Esophagitis

Papillary Conjunctivitis

Asthma

Chronic Obstructive Asthma	Asthma, Diminished Response To Antileukotriene Treatment In
Bronchial Hyperreactivity	Asthma, Susceptibility To
Asthma, Bronchial	Asthma, Protection Against
Asthma, Nocturnal, Susceptibility To	Nocturnal Asthma
Asthma-Related Traits	Asthma-Related Traits, Susceptibility To
Asthma, Nocturnal	Chronic Obstructive Asthma With Acute Exacerbation
Chronic Obstructive Asthma With Status Asthmaticus	Exercise Induced Asthma
Exercise-Induced Asthma	Bronchial Asthma
Asthma, Exercise-Induced	Idiosyncratic Asthma
Unspecified Asthma With Acute Exacerbation	Asthma, Unspecified, With Stated Status Asthmaticus
Status Asthmaticus Nos	Acute Severe Asthma
Acute Severe Bronchial Asthma	Status Asthma
Status Post Asthmaticus

Conjunctivitis

Madras Eye	Adenoviral Conjunctivitis
Acute Adenoviral Follicular Conjunctivitis	Inclusion Conjunctivitis Of The Adult
Swimming-Pool Conjunctivitis	Inflammation Of Conjunctiva
Ophthalmia	Acute Conjunctivitis
Eye Catarrh	Catarrhal Ophthalmia
Koch-Weeks Conjunctivitis

Giant Papillary Conjunctivitis

Gpc	Conjunctivitis Giant Papillary
Conjunctivitis, Giant Papillary	Chronic Giant Papillary Conjunctivitis
Chronic Papillary Conjunctivitis

Esophagitis, Eosinophilic, 1

Eosinophilic Esophagitis	EOE1
Esophagitis, Eosinophilic	Ee

Eosinophilic Gastritis

Eosinophilic Enteropathy

Angiostrongyliasis

A. Cantonensis Angiostrongyliasis

Chronic Asthma

Respiratory Allergy

Airway Allergy

Bronchial Disease

Bronchial Diseases	Bronchial Disorders
Bronchial Spasm

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02094	CCL24 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CCL24	VGNC	VGNC:38886
Macaca mulatta	CCL24	VGNC	VGNC:80856
Mus musculus	CCL24	MGD	MGI:1928953
Bos taurus	CCL24	VGNC	VGNC:26950
Felis catus	CCL24	VGNC	VGNC:60544
Rattus norvegicus	CCL24	RGD	RGD:1310245
Macaca fascicularis	CCL24	NCBI
Others	CCL24	NCBI

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