Ephb4 - EPH receptor B4 Gene

Predicted to enable transmembrane-ephrin receptor activity. Predicted to be involved in several processes, including circulatory system development; Ephrin Receptor signaling pathway; and protein autophosphorylation. Predicted to act upstream of or within positive regulation of T cell costimulation; positive regulation of aorta morphogenesis; and venous blood vessel morphogenesis. Predicted to be part of receptor complex. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human EphB4 (EPH receptor B4). [provided by Alliance of Genome Resources, Apr 2022]