Prmt3 - protein arginine N-methyltransferase 3 Gene

Also Known as Hrmt1l3; 2010005E20Rik; 2410018A17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71974

About Prmt3

Chromosome 7: 49,428,094-49,508,013 forward strand.GRCm39:CM001000.3

This gene has 9 transcripts (splice variants), 205 orthologues, 7 paralogues and is associated with 21 phenotypes. Ubiquitous expression in ovary adult (RPKM 18.2), CNS E11.5 (RPKM 14.1) and 28 other tissues.

Summary

Enables protein-arginine N-methyltransferase activity and ribosome binding activity. Involved in protein methylation. Located in cytosol. Is expressed in several structures, including central nervous system; genitourinary system; liver; sensory organ; and spleen. Orthologous to human PRMT3 (protein arginine methyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]

Prmt3 Products (1)

mRNA Protein Name
NM_133740.2 NP_598501.1 protein arginine N-methyltransferase 3

Prmt3 Protein Structure

zf-C2H2_2

zf-C2H2_2: cl20464 (47 - 96)

AdoMet_MTases

AdoMet_MTases: cd02440 (255 - 355)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 528 a.a.
Protein Preferred Names Protein Names

protein arginine N-methyltransferase 3

  • heterogeneous nuclear ribonucleoprotein methyltransferase-like 3

  • heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3

  • protein arginine methyltransferase 3

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-128717 GSK3368715 Inhibitor 99.41% Phase 1

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19615 MS023 Inhibitor 99.93% Unkown
HY-128717A GSK3368715 dihydrochloride Inhibitor 99.96% Unkown
HY-19715 SGC707 Inhibitor 99.99% Unkown
HY-19615B MS023 dihydrochloride Inhibitor 99.68% Unkown
HY-141877 MS4322 Degrader 99.14% Unkown
HY-141877B MS4322 (isomer) 99.87% Unkown
HY-128717B GSK3368715 trihydrochloride Inhibitor / Unkown
HY-161334 CARM1-IN-4 Inhibitor / Unkown
HY-159732 PRMT3-IN-4 Inhibitor / Unkown
HY-184653 MS3-123 Inhibitor / Unkown
HY-159728 PROTAC PRMT3 degrader 1 Degrader / Unkown
HY-146810 PRMT4-IN-1 Inhibitor / Unkown
HY-110158 UNC2327 Inhibitor 99.70% Unkown
HY-171132 PRMT3-IN-5 Inhibitor / Unkown
HY-175821 PRMT1-IN-3 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prmt3 NCBI NCBI:10196