ZNF205 - zinc finger protein 205 Gene

Also Known as RhitH; Zfp13; ZNF210

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7755

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of hydrogen peroxide biosynthetic process; and positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrion and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in kidney (RPKM 3.3), ovary (RPKM 2.9) and 25 other tissues.

ZNF205 Products (3)

mRNA Protein Name
NM_001042428.2 NP_001035893.1 transcriptional repressor RHIT
NM_001278158.2 NP_001265087.1 transcriptional repressor RHIT
NM_003456.3 NP_003447.2 transcriptional repressor RHIT

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16713569 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
22306510 GOA
involved in positive regulation of hydrogen peroxide biosynthetic process IMP
IMP: Inferred from mutant phenotype
22306510 GOA
involved in positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
22306510 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF205 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF205 O95201 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
ZNF205 O95201 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
ZNF205 O95201 UBQLN4 Homo sapiens Q9NRR5
Y2H Array
16713569
Intra
ZNF205 O95201 TSGA10 Homo sapiens Q9BZW7
Validated Y2H
32296183
Intra
ZNF205 O95201 TSGA10 Homo sapiens Q9BZW7
Y2H Prey Pooling
32296183
Intra
ZNF205 O95201 TSGA10 Homo sapiens Q9BZW7
Y2H Array
32296183
Intra
ZNF205 O95201 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
ZNF205 O95201 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
ZNF205 O95201 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
ZNF205 O95201 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra
ZNF205 O95201 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Intra
ZNF205 O95201 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Intra
ZNF205 O95201 TNS2 Homo sapiens Q63HR2
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16109 ZNF207 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16112 ZNF225 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16438 ZNF605 Human Pre-designed siRNA Set A Pre-designed Set / Unkown