CCDC68 - coiled-coil domain containing 68 Gene

Also Known as SE57-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80323

Summary

Involved in intracellular protein localization and microtubule anchoring at centrosome. Located in centriole. Part of centriolar subdistal appendage. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in placenta (RPKM 6.2), small intestine (RPKM 5.9) and 20 other tissues.

CCDC68 Products (2)

mRNA Protein Name
NM_001143829.2 NP_001137301.1 coiled-coil domain-containing protein 68
NM_025214.3 NP_079490.1 coiled-coil domain-containing protein 68

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in microtubule anchoring at centrosome IGI
IGI: Inferred from genetic interaction
28422092 GOA
involved in microtubule anchoring at centrosome IMP
IMP: Inferred from mutant phenotype
28422092 GOA
involved in protein localization IMP
IMP: Inferred from mutant phenotype
28422092 GOA
Cellular Component GO Annotation Evidence References Source
part of centriolar subdistal appendage IDA
IDA: Inferred from direct assay
28422092 GOA
located in centriole IDA
IDA: Inferred from direct assay
28422092 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCDC68 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CCDC68 Q9H2F9 CEP170 Homo sapiens Q5SW79
Anti Tag CoIP
28422092
Intra
CCDC68 Q9H2F9 CEP170 Homo sapiens Q5SW79
Anti Bait CoIP
28422092
Intra
CCDC68 Q9H2F9 CEP170 Homo sapiens Q5SW79
Confocal
28422092
Intra
CCDC68 Q9H2F9 CEP170 Homo sapiens Q5SW79
Anti Tag CoIP
33961781
Intra
CCDC68 Q9H2F9 CEP170 Homo sapiens Q5SW79
Anti Tag CoIP
28514442
Intra
CCDC68 Q9H2F9 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra
CCDC68 Q9H2F9 TFIP11 Homo sapiens Q9UBB9
Y2H Array
25416956
Intra
CCDC68 Q9H2F9 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
CCDC68 Q9H2F9 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
CCDC68 Q9H2F9 TFIP11 Homo sapiens Q9UBB9
Y2H Array
31515488
Intra
CCDC68 Q9H2F9 DYNLT1 Homo sapiens P63172
Y2H Prey Pooling
32296183
Intra
CCDC68 Q9H2F9 DYNLT1 Homo sapiens P63172
Y2H Array
32296183
Intra
CCDC68 Q9H2F9 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra
CCDC68 Q9H2F9 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11118A Biotinylated CCDC61 peptide TFA 99.90% Unkown
HY-P11118 Biotinylated CCDC61 peptide / Unkown
HY-RS02038 CCDC18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02051 CCDC6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02052 CCDC66 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02053 CCDC69 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02056 CCDC78 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02057 CCDC8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02060 CCDC86 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20872 Ccdc6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27389 Ccdc6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown