Mtr - 5-methyltetrahydrofolate-homocysteine methyltransferase Gene

Also Known as methioninesynthase

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81522

Summary

Enables amino acid binding activity; folic acid binding activity; and methionine synthase activity. Involved in several processes, including alpha-amino acid metabolic process; cellular response to methionine; and cellular response to nitric oxide. Predicted to be active in cytosol. Biomarker of type 2 diabetes mellitus and vitamin B12 deficiency. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; hematologic Cancer (multiple); hyperhomocysteinemia; and methylmalonic aciduria and homocystinuria type cblG. Orthologous to human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Mtr Products (1)

mRNA Protein Name
NM_030864.2 NP_110491.2 methionine synthase
Protein Preferred Names Protein Names

methionine synthase

  • MS

  • cobalamin-dependent methionine synthase

  • vitamin-B12 dependent methionine synthase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-156048 Trifluoromethyl-tubercidin Inhibitor 99.90% Unkown
HY-12892 SKI-178 99.29% Unkown
HY-116688 2-Hydroxy-4-(methylthio)butyric acid 88.0% Unkown
HY-148953 MTR-106 98.21% Unkown
HY-W077219 Boc-L-Arg(Mtr)-OH 99.06% Unkown
HY-RS08815 MTR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17417 Terc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18898 Mtr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25389 Mtr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mtr NCBI NCBI:4548