2. Gene
  3. SLC14A2 - solute carrier family 14 member 2 Gene

SLC14A2 - solute carrier family 14 member 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as UT2; UTA; UTR; HUT2; UT-A2; hUT-A6

Gene ID: 8170 | Gene type: protein coding

About SLC14A2

Cytogenetic location: 18q12.3 Genomic coordinates (GRCh38): 18:45,167,963-45,683,688 (from NCBI)

This gene has 3 transcripts (splice variants), 251 orthologues and 1 paralogue. Biased expression in kidney (RPKM 2.6), fat (RPKM 1.3) and 7 other tissues.

Summary

The protein encoded by this gene belongs to the Urea Transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]

SLC14A2 Products(3)

mRNA Protein Name
NM_001242692.2 NP_001229621.1 urea transporter 2
NM_001371319.1 NP_001358248.1 urea transporter 2
NM_007163.4 NP_009094.3 urea transporter 2

SLC14A2 Protein Structure

UT

UT: Urea transporter (117 - 420)

UT

UT: Urea transporter (579 - 883)

  • 0
  • 200
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  • 600
  • 800
  • 920 a.a.
Protein Preferred Names Protein Names

urea transporter 2

solute carrier family 14 (urea transporter), member 2

Related Diseases

Diseases Alias
Bone Chondrosarcoma
Yaws

Frambesia

Frambesia Tropica

Bouba

Frambosie

Polypapilloma Tropicum

Thymosis

Endemic Treponematoses

Treponema Pertenue Infection

Pian

Framboesia

Framboesia Tropica

Castellani

Infection By Treponema Pertenue

Parangi

Framboesioma

Chancre Of Yaws

Primary Framboesia

Initial Lesions Of Yaws

Mother Yaw

Initial Framboesia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13011 SLC14A2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SLC14A2 VGNC VGNC:77392
Mus musculus SLC14A2 MGD MGI:1351653
Bos taurus SLC14A2 VGNC VGNC:34678
Canis familiaris SLC14A2 VGNC VGNC:49648
Rattus norvegicus SLC14A2 RGD RGD:3689