ZNF496 - zinc finger protein 496 Gene

Also Known as NIZP1; ZFP496; ZSCAN49; ZKSCAN17

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84838

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in positive regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in nuclear body. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in testis (RPKM 3.4), ovary (RPKM 3.0) and 25 other tissues.

ZNF496 Products (2)

mRNA Protein Name
NM_001329733.2 NP_001316662.1 zinc finger protein 496 isoform 2
NM_032752.3 NP_116141.1 zinc finger protein 496 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF496 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF496 Q96IT1 ZSCAN22 Homo sapiens P10073
Validated Y2H
25416956
Intra
ZNF496 Q96IT1 ZSCAN22 Homo sapiens P10073
Y2H Array
31515488
Intra
ZNF496 Q96IT1 ZNF483 Homo sapiens Q6P088
Y2H Array
25416956
Intra
ZNF496 Q96IT1 ZSCAN21 Homo sapiens Q9Y5A6
Y2H Prey Pooling
25416956
Intra
ZNF496 Q96IT1 ZSCAN21 Homo sapiens Q9Y5A6
Validated Y2H
32296183
Intra
ZNF496 Q96IT1 ZSCAN21 Homo sapiens Q9Y5A6
Y2H Array
25416956
Intra
ZNF496 Q96IT1 PGBD1 Homo sapiens Q96JS3
Validated Y2H
32296183
Intra
ZNF496 Q96IT1 ZSCAN12 Homo sapiens O43309
Validated Y2H
25416956
Intra
ZNF496 Q96IT1 ZSCAN12 Homo sapiens O43309
Y2H Array
25416956
Intra
ZNF496 Q96IT1 ZKSCAN4 Homo sapiens Q969J2
Y2H Array
31515488
Intra
ZNF496 Q96IT1 ZKSCAN4 Homo sapiens Q969J2
Validated Y2H
25416956
Intra
ZNF496 Q96IT1 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
ZNF496 Q96IT1 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra
ZNF496 Q96IT1 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
ZNF496 Q96IT1 ARR3 Homo sapiens P36575
Y2H Array
25416956
Intra
ZNF496 Q96IT1 ARR3 Homo sapiens P36575
Validated Y2H
25416956
Intra
ZNF496 Q96IT1 ARR3 Homo sapiens P36575
Y2H Prey Pooling
25416956
Intra
ZNF496 Q96IT1 ZNF446 Homo sapiens Q9NWS9-2
Y2H Prey Pooling
25416956
Intra
ZNF496 Q96IT1 ZNF446 Homo sapiens Q9NWS9-2
Validated Y2H
32296183
Intra
ZNF496 Q96IT1 ZNF446 Homo sapiens Q9NWS9-2
Y2H Array
25416956
Intra
ZNF496 Q96IT1 SCAND1 Homo sapiens P57086
Anti Tag CoIP
31403225
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16140 ZNF436 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16146 ZNF469 Human Pre-designed siRNA Set A Pre-designed Set / Unkown