2. Gene
  3. SNX4 - sorting nexin 4 Gene

SNX4 - sorting nexin 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as ATG24B

Gene ID: 8723 | Gene type: protein coding

About SNX4

Cytogenetic location: 3q21.2 Genomic coordinates (GRCh38): 3:125,446,650-125,520,202 (from NCBI)

This gene has 5 transcripts (splice variants), 204 orthologues and 15 paralogues. Ubiquitous expression in thyroid (RPKM 29.2), kidney (RPKM 26.4) and 25 other tissues.

Summary

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the Leptin receptor and with Receptor Tyrosine Kinases for platelet-derived growth factor, Insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012]

SNX4 Products(1)

mRNA Protein Name
NM_003794.4 NP_003785.1 sorting nexin-4

SNX4 Protein Structure

PX

PX: PX domain (59 - 183)

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Protein Preferred Names Protein Names

sorting nexin-4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13543 SNX4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SNX4 VGNC VGNC:35111
Mus musculus SNX4 MGD MGI:1916400
Rattus norvegicus SNX4 RGD RGD:1309763
Macaca mulatta SNX4 VGNC VGNC:77684
Canis familiaris SNX4 VGNC VGNC:46641
Felis catus SNX4 VGNC VGNC:65557