Amn - amnionless Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 93835

Summary

This gene encodes a type I transmembrane protein. The encoded protein is an essential component of the cubulin receptor complex which is thought to play a role in coordinating growth and patterning of the embryo. This protein is thought to modulate a bone morphogenetic protein (BMP) signaling pathway. A homoygous mutation in the mouse gene results in the lack of an amnion in embryos. Mutations in the human gene are associated with Megaloblastic Anemia-1. [provided by RefSeq, Sep 2015]

Amn Products (1)

mRNA Protein Name
NM_033603.3 NP_291081.2 protein amnionless precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
15342463 MGI
acts upstream of or within renal protein absorption IMP
IMP: Inferred from mutant phenotype
15342463 MGI
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
15342463 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein amnionless

  • type I transmembrane protein

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10159 Nilotinib 99.94% Yes
HY-10159A Nilotinib monohydrochloride monohydrate 99.91% Yes
HY-10159B Nilotinib hydrochloride 99.86% Yes

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103565 AMN082 Agonist 99.73% Unkown
HY-10159S Nilotinib-d6 99.95% Unkown
HY-10159C Nilotinib hydrochloride dihydrate 99.89% Unkown
HY-RS00068 ABCD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-103565A AMN082 free base Agonist 98.37% Unkown
HY-10159S1 Nilotinib-13C,d3 / Unkown
HY-RS00661 AMN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00662 AMN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-134360A ATP-1-Aminonaphthalene-5-sulfonate sodium / Unkown
HY-137604A (γ-AmNS)UTP trisodium / Unkown
HY-137678A GTP-γ-AmNS trisodium / Unkown
HY-168917 9-Aminominocycline Inhibitor / Unkown
HY-RS17996 Traf3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18731 Amn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25218 Amn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amn NCBI NCBI:81693