CD302 - CD302 molecule Gene

Also Known as DCL1; DCL-1; BIMLEC; CLEC13A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9936

About CD302

Cytogenetic location: 2q24.2 Genomic coordinates (GRCh38): 2:159,768,628-159,798,208 (from NCBI)

This gene has 4 transcripts (splice variants), 189 orthologues and 4 paralogues. Ubiquitous expression in liver (RPKM 51.3), lung (RPKM 34.3) and 25 other tissues.

Summary

CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis (Kato et al., 2007 [PubMed 17947679]).[supplied by OMIM, Aug 2008]

CD302 Products (3)

mRNA Protein Name
NM_001198763.2 NP_001185692.1 CD302 antigen isoform 2 precursor
NM_001198764.2 NP_001185693.1 CD302 antigen isoform 3 precursor
NM_014880.5 NP_055695.2 CD302 antigen isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within phagocytosis IDA
IDA: Inferred from direct assay
17947679 GOA
Cellular Component GO Annotation Evidence References Source
located in cell cortex IDA
IDA: Inferred from direct assay
17947679 GOA
located in filopodium IDA
IDA: Inferred from direct assay
17947679 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CD302 Protein Structure

Lectin_C

Lectin_C: Lectin C-type domain (47 - 147)

  • 0
  • 100
  • 200
  • 232 a.a.
Protein Preferred Names Protein Names

CD302 antigen

  • C-type lectin domain family 13, member A

CD302 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CD302 Q8IX05 IL10RA Homo sapiens Q13651
Y2H Prey Pooling
32296183
Intra
CD302 Q8IX05 IL10RA Homo sapiens Q13651
Y2H Array
32296183
Intra
CD302 Q8IX05 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra
CD302 Q8IX05 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra
CD302 Q8IX05 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra
CD302 Q8IX05 GPX8 Homo sapiens Q8TED1
Validated Y2H
32296183
Intra
CD302 Q8IX05 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra
CD302 Q8IX05 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra
CD302 Q8IX05 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra
CD302 Q8IX05 FNDC9 Homo sapiens Q8TBE3
Validated Y2H
32296183
Intra
CD302 Q8IX05 OPRM1 Homo sapiens P35372-10
Y2H Array
32296183
Intra
CD302 Q8IX05 OPRM1 Homo sapiens P35372-10
Y2H Prey Pooling
32296183
Intra
CD302 Q8IX05 GET1 Homo sapiens O00258
Y2H Prey Pooling
32296183
Intra
CD302 Q8IX05 GET1 Homo sapiens O00258
Y2H Array
32296183
Intra
CD302 Q8IX05 IFNGR2 Homo sapiens P38484
Y2H Array
32296183
Intra
CD302 Q8IX05 IFNGR2 Homo sapiens P38484
Y2H Prey Pooling
32296183
Intra
CD302 Q8IX05 CD53 Homo sapiens P19397
Y2H Prey Pooling
32296183
Intra
CD302 Q8IX05 CD53 Homo sapiens P19397
Y2H Array
32296183
Intra
CD302 Q8IX05 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra
CD302 Q8IX05 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra
CD302 Q8IX05 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra
CD302 Q8IX05 IL7R Homo sapiens P16871
Y2H Array
32296183
Intra
CD302 Q8IX05 IL7R Homo sapiens P16871
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Hyperinsulinemic Hypoglycemia, Familial, 3

  • HHF3

  • Hyperinsulinism Due To Glucokinase Deficiency

  • Familial Hyperinsulinemic Hypoglycemia 3

  • Hyperinsulinemic Hypoglycemia Due To Glucokinase Deficiency

  • Hyperinsulinemic Hypoglycemia Familial 3

  • Congenital Hyperinsulinism

  • Persistent Hyperinsulinemic Hypoglycemia Of Infancy

  • Phhi

  • Hypoglycemia, Hyperinsulinemic, Familial, Type 3
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02233 CD302 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18652 Cd302 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25138 Cd302 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CD302 VGNC VGNC:55333
Rattus norvegicus CD302 RGD RGD:1307606
Mus musculus CD302 MGD MGI:1913455