Germacrone 4,5-epoxide
Germacrone 4,5-epoxide is a sesquiterpene that can be isolated from Curcuma cf. viridiflora. Germacrone 4,5-epoxide has excellent anti-leukemic activities.
For research use only. We do not sell to patients.
- CAS No.: 92691-35-5
- Formula: C15H22O2
- Molecular Weight:234.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HT-29 | IC50 |
39.6 μg/mL
Compound: 3
|
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 29274817] |
| HUVEC | IC50 |
48.4 μg/mL
Compound: 3
|
Cytotoxicity against human HUVEC cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HUVEC cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 29274817] |
| KG-1a | IC50 |
>100 μg/mL
Compound: 3
|
Cytotoxicity against human KG1a cells assessed as reduction in cell viability after 48 hrs by MTT assay
Cytotoxicity against human KG1a cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 29274817] |
| MCF7 | IC50 |
37.2 μg/mL
Compound: 3
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 29274817] |
| PC-3 | IC50 |
43.9 μg/mL
Compound: 3
|
Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 29274817] |
Chemical Information
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CAS No. 92691-35-5
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Molecular Weight 234.33
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Formula C15H22O2
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SMILES
C[C@]1(CC/C=C2C)[C@@](C/C(C(C\2)=O)=C(C)/C)([H])O1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)