2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. GGFG-Eribulin

GGFG-Eribulin (Compound GGFG) is a Drug-Linker Conjugates for ADC. GGFG-Eribulin consists of the ADC Cytotoxin Eribulin (HY-13442) and a linker. GGFG-Eribulin can be used for synthesis of ADCs.

For research use only. We do not sell to patients.

GGFG-Eribulin Chemical Structure

GGFG-Eribulin Chemical Structure

CAS No. : 2841688-66-0

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1 mg USD 484 In-stock
5 mg USD 1065 In-stock
10 mg USD 1700 In-stock
25 mg USD 3570 In-stock
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Based on 1 publication(s) in Google Scholar

GGFG-Eribulin Related Antibodies

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Description

GGFG-Eribulin (Compound GGFG) is a Drug-Linker Conjugates for ADC. GGFG-Eribulin consists of the ADC Cytotoxin Eribulin (HY-13442) and a linker. GGFG-Eribulin can be used for synthesis of ADCs[1].

Molecular Weight

1048.22

Formula

C55H77N5O15
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C=C1C[C@](O[C@@]1([H])CC[C@](C[C@H]2C)([H])O[C@](C2=C)([H])C[C@@](O[C@@H]3C[C@H](O)CNC(CNC([C@@H](NC(CNC(CN)=O)=O)CC4=CC=CC=C4)=O)=O)([H])[C@]([C@H]3OC)([H])CC5=O)([H])CC[C@@]6(C[C@@]7([H])O8)O[C@]([C@](O[C@](C5)([H])CC9)([H])[C@@]9([H])O%10)([H])[C@@]8([H])[C@]%10([H])[C@@]7([H])O6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (95.40 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9540 mL 4.7700 mL 9.5400 mL
5 mM 0.1908 mL 0.9540 mL 1.9080 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9540 mL 4.7700 mL 9.5400 mL 23.8500 mL
5 mM 0.1908 mL 0.9540 mL 1.9080 mL 4.7700 mL
10 mM 0.0954 mL 0.4770 mL 0.9540 mL 2.3850 mL
15 mM 0.0636 mL 0.3180 mL 0.6360 mL 1.5900 mL
20 mM 0.0477 mL 0.2385 mL 0.4770 mL 1.1925 mL
25 mM 0.0382 mL 0.1908 mL 0.3816 mL 0.9540 mL
30 mM 0.0318 mL 0.1590 mL 0.3180 mL 0.7950 mL
40 mM 0.0238 mL 0.1192 mL 0.2385 mL 0.5962 mL
50 mM 0.0191 mL 0.0954 mL 0.1908 mL 0.4770 mL
60 mM 0.0159 mL 0.0795 mL 0.1590 mL 0.3975 mL
80 mM 0.0119 mL 0.0596 mL 0.1192 mL 0.2981 mL
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GGFG-Eribulin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GGFG-Eribulin2841688-66-0Drug-Linker Conjugates for ADCcancerADCsEribulinInhibitorinhibitorinhibit

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