GJ103
Based on 1 publication(s) in Google Scholar
GJ103 is a read-through compound that can induce read through of premature stop codons. GJ103 has potential for the research of genetic disorders caused by nonsense mutations.
For research use only. We do not sell to patients.
- Purity: 99.33%
- CAS No.: 1459687-89-8
- Formula: C16H14N4O3S
- Molecular Weight:342.37
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) GJ103
More
Biological Activity
GJ103 does not show obvious cytotoxicity in A-T cells at concentration as high as 300 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1459687-89-8
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Appearance Solid
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Molecular Weight 342.37
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Formula C16H14N4O3S
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SMILES
OC(CSC1=NN=C(N1C2=CC=CC(OC)=C2)C3=NC=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
Meis1 Targets Protein Tyrosine Phosphatase Receptor J in Fibroblast to Retard Chronic Kidney Disease Progression. [Abstract]2024 Aug 20:e2309754. PMID: 39162106
Solvent & Solubility
DMSO : 31.25 mg/mL (91.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9208 mL | 14.6041 mL | 29.2082 mL | 73.0204 mL |
| 5 mM | 0.5842 mL | 2.9208 mL | 5.8416 mL | 14.6041 mL | |
| 10 mM | 0.2921 mL | 1.4604 mL | 2.9208 mL | 7.3020 mL | |
| 15 mM | 0.1947 mL | 0.9736 mL | 1.9472 mL | 4.8680 mL | |
| 20 mM | 0.1460 mL | 0.7302 mL | 1.4604 mL | 3.6510 mL | |
| 25 mM | 0.1168 mL | 0.5842 mL | 1.1683 mL | 2.9208 mL | |
| 30 mM | 0.0974 mL | 0.4868 mL | 0.9736 mL | 2.4340 mL | |
| 40 mM | 0.0730 mL | 0.3651 mL | 0.7302 mL | 1.8255 mL | |
| 50 mM | 0.0584 mL | 0.2921 mL | 0.5842 mL | 1.4604 mL | |
| 60 mM | 0.0487 mL | 0.2434 mL | 0.4868 mL | 1.2170 mL | |
| 80 mM | 0.0365 mL | 0.1826 mL | 0.3651 mL | 0.9128 mL |
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