Glasdegib hydrochloride
Based on 5 publication(s) in Google Scholar
Glasdegib hydrochloride is a potent and orally bioavailable smoothened inhibitor. Glasdegib hydrochloride (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM.
For research use only. We do not sell to patients.
- CAS No.: 1095173-64-0
- Formula: C21H23ClN6O
- Molecular Weight:410.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Glasdegib hydrochloride
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Biological Activity
Chemical Information
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CAS No. 1095173-64-0
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Molecular Weight 410.90
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Formula C21H23ClN6O
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SMILES
CN1[C@H](C[C@@H](CC1)NC(NC2=CC=C(C=C2)C#N)=O)C3=NC4=CC=CC=C4N3.Cl
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Synonyms
PF-04449913 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (5)
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Journal Impact Factor
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Most Recent
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Molecules
Development and Validation of a Rapid LC-MS/MS Method for Quantifying Alvocidib: In Silico and In Vitro Metabolic Stability Estimation in Human Liver Microsomes. [Abstract]2023 Mar 4;28(5):2368. PMID: 36903615 -
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Methods Mol Biol
2018:1711:351-398. PMID: 29344898
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)