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Art. -Nr.: HY-163530

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GPR41 modulator 1

GPR41 modulator 1 (compound 10ak) is a potent GPR41 modulator with an EC₅₀ value of 0.679 µM. GPR41 modulator 1 shows agonistic modulator activity.

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CAS. Nr.: 3050768-93-6
Formel: C₂₈H₂₄F₂N₂O₃
Molecular Weight:474.50

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

GPR41 modulator 1 Chemical Structure

CAS. Nr.: 3050768-93-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

GPR41 modulator 1 (compound 10ak) is a potent GPR41 modulator with an EC₅₀ value of 0.679 µM. GPR41 modulator 1 shows agonistic modulator activity^[1].

IC₅₀ & Target

EC₅₀: 0.679 µM (GPR41)^[1]

Alle Free Fatty Acid Receptor Isoform-spezifische Produkte anzeigen :

In Vitro

GPR41 modulator 1 (compound 10ak) (1 µM) decreases the cAMP level induced by propionate (10 mM) in HEK293 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3050768-93-6
Molecular Weight 474.50
Formel C₂₈H₂₄F₂N₂O₃
SMILES

FC1=CC(F)=CC(C2=CC=C(O2)C3C(C(NC4=C(C=CC=C4)C)=O)=C(NC5=C3C(CCC5)=O)C)=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Inuki S, et al. Structure-activity relationship studies of tetrahydroquinolone derivatives as GPR41 modulators. Bioorg Med Chem Lett. 2024 Jul 15;107:129758. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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