2. GPCR/G Protein
  3. GPR84
  4. GPR84 agonist-2

GPR84 agonist-2 is a selective GPR84 agonist with no activity at free fatty acid receptors. GPR84 agonist-2 enhances GPR84-mediated signaling above basal levels and potentiates agonist-induced GPR84 activation. GPR84 agonist‑2 can be used for research on GPR84-related physiological mechanisms.

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GPR84 agonist-2

GPR84 agonist-2 Chemical Structure

CAS No. : 3105662-82-3

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Based on 1 publication(s) in Google Scholar

GPR84 agonist-2 Related Antibodies

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Description

GPR84 agonist-2 is a selective GPR84 agonist with no activity at free fatty acid receptors. GPR84 agonist-2 enhances GPR84-mediated signaling above basal levels and potentiates agonist-induced GPR84 activation. GPR84 agonist‑2 can be used for research on GPR84-related physiological mechanisms[1].

In Vitro

GPR84 agonist‑2 (compound 8e) acts as a full agonist at human GPR84 with a pEC50 of 6.24 and 100% efficacy, and exhibits no inverse agonistic or antagonistic activity in the PRESTO‑Tango β‑arrestin recruitment assay[1].
GPR84 agonist-2 are selective, showing no significant activity on related free fatty acid receptors FFA1, FFA2, FFA3, or FFA4[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GPR84 agonist-2 Related Antibodies
Molecular Weight

333.51

Formula

C21H35NO2
CAS No.
Appearance

Oil

Color

Yellow to brown

SMILES

OC1=CC(OCC2CCCCC2)=NC(CCCCCCCCC)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation
References
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GPR84 agonist-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GPR84 agonist-23105662-82-3GPR84G protein coupled receptor 84respiratory burstFFA26-OAUFFA3neutrophilshuman neutrophilsIL-8FFA1LPSInhibitorinhibitorinhibit

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GPR84 agonist-2
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