GW409544
GW409544 is a potent PPARα and PPARγ activator, with EC50 values of 2.3 nM and 0.28 nM for PPARα and PPARγ, respectively. GW409544 can be used for the research of metabolic and cardiovascular diseases.
For research use only. We do not sell to patients.
- CAS No.: 258345-41-4
- Formula: C31H30N2O5
- Molecular Weight:510.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PPARα 2.3 nM (EC50) |
PPAR-γ 0.28 nM (EC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
0.0027 μM
Compound: GW-409544
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Agonist activity at human GAL4-tagged PPARgamma chimeric receptor expressed in HEK cells by transactivation assay
Agonist activity at human GAL4-tagged PPARgamma chimeric receptor expressed in HEK cells by transactivation assay
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[PMID: 20299214] |
| HEK293 | EC50 |
0.01 μM
Compound: GW-409544
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Agonist activity at human GAL4-tagged PPARalpha chimeric receptor expressed in HEK cells by transactivation assay
Agonist activity at human GAL4-tagged PPARalpha chimeric receptor expressed in HEK cells by transactivation assay
|
[PMID: 20299214] |
Chemical Information
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CAS No. 258345-41-4
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Molecular Weight 510.58
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Formula C31H30N2O5
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SMILES
O=C(C1=CC=CC=C1)/C=C(C)\N[C@H](C(O)=O)CC(C=C2)=CC=C2OCCC3=C(C)OC(C4=CC=CC=C4)=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GW409544 Related Classifications
HY-121448 Related Classifications
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