1. Others Neuronal Signaling
  2. Fluorescent Dye Amyloid-β
  3. h-FTAA

h-FTAA is a luminescent conjugated oligothiophene (LCO) probe. h-FTAA can selectively bind to amyloid protein aggregates (such as plaques) and distinguish different conformations of the protein aggregates through changes in fluorescence signals. h-FTAA significantly reduces the neurotoxicity of Aβ1-42 and the Arctic mutant Aβ (AβArc), thereby protecting SH-SY5Y neuroblastoma cells. h-FTAA can be used to dynamically track the formation and maturation process of Aβ plaques.

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h-FTAA

h-FTAA Chemical Structure

CAS No. : 1352477-26-9

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Description

h-FTAA is a luminescent conjugated oligothiophene (LCO) probe. h-FTAA can selectively bind to amyloid protein aggregates (such as plaques) and distinguish different conformations of the protein aggregates through changes in fluorescence signals. h-FTAA significantly reduces the neurotoxicity of Aβ1-42 and the Arctic mutant Aβ (AβArc), thereby protecting SH-SY5Y neuroblastoma cells. h-FTAA can be used to dynamically track the formation and maturation process of Aβ plaques[1][2].

Molecular Weight

780.97

Formula

C34H20O8S7

CAS No.
SMILES

O=C(C1=CC=C(C2=CC=C(C3=CC(CC(O)=O)=C(C4=CC=C(C5=C(CC(O)=O)C=C(C6=CC=C(C7=CC=C(C(O)=O)S7)S6)S5)S4)S3)S2)S1)O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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h-FTAA
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