HaloAUTAC tt15
Based on 1 Customer Validation
HaloAUTAC tt15 is an autophagy-targeting chimera (AUTAC), that targets the Halo Tag carrying proteins, and degrades via the autophagy mechanism.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 96.28%
- CAS 番号: 2241668-45-9
- 分子式: C33H49Cl2N7O8S
- 分子量:774.76
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
体外実験
HaloAUTAC tt15 (1 μM, 24 h) degrades EGFP-HT protein (enhanced green fluorescence protein-fused HaloTag) in HeLa cell[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2241668-45-9
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性状 Solid
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分子量 774.76
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分子式 C33H49Cl2N7O8S
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Color White to light yellow
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SMILES
ClCCCCCCOCCOCCOCCOCCOCCNC([C@@H](NC(C)=O)CSC1=NC(C(N=C(N2)N)=O)=C2N1CC3=CC=C(C=C3)Cl)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (129.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2907 mL | 6.4536 mL | 12.9072 mL | 32.2681 mL |
| 5 mM | 0.2581 mL | 1.2907 mL | 2.5814 mL | 6.4536 mL | |
| 10 mM | 0.1291 mL | 0.6454 mL | 1.2907 mL | 3.2268 mL | |
| 15 mM | 0.0860 mL | 0.4302 mL | 0.8605 mL | 2.1512 mL | |
| 20 mM | 0.0645 mL | 0.3227 mL | 0.6454 mL | 1.6134 mL | |
| 25 mM | 0.0516 mL | 0.2581 mL | 0.5163 mL | 1.2907 mL | |
| 30 mM | 0.0430 mL | 0.2151 mL | 0.4302 mL | 1.0756 mL | |
| 40 mM | 0.0323 mL | 0.1613 mL | 0.3227 mL | 0.8067 mL | |
| 50 mM | 0.0258 mL | 0.1291 mL | 0.2581 mL | 0.6454 mL | |
| 60 mM | 0.0215 mL | 0.1076 mL | 0.2151 mL | 0.5378 mL | |
| 80 mM | 0.0161 mL | 0.0807 mL | 0.1613 mL | 0.4034 mL | |
| 100 mM | 0.0129 mL | 0.0645 mL | 0.1291 mL | 0.3227 mL |