HDAC8-IN-1 (Standard)
HDAC8-IN-1 (Standard) is the analytical standard of HDAC8-IN-1 (HY-111342). This product is intended for research and analytical applications. HDAC8-IN-1 is a HDAC8 inhibitor with an IC50 of 27.2 nM.
For research use only. We do not sell to patients.
- CAS No.: 1417997-93-3
- Formula: C22H19NO3
- Molecular Weight:345.39
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 1417997-93-3
-
Molecular Weight 345.39
-
Formula C22H19NO3
-
SMILES
O=C(NO)/C=C/C1=CC=C(OC)C=C1C2=CC=C(C3=CC=CC=C3)C=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Huang WJ, et al. Synthesis and biological evaluation of ortho-aryl N-hydroxycinnamides as potent histone deacetylase (HDAC) 8 isoform-selective inhibitors. ChemMedChem. 2012 Oct;7(10):1815-24. [Content Brief]
[2]. Cui J, et al., IL-4 inhibits regulatory T cells differentiation by HDAC9-mediated epigenetic regulation. Cell Death Dis. 2021 May 18;12(6):501. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)