Hericenone A
Hericenone A is an isoindolinone found in the fruiting bodies of Hericium erinaceus. Hericenone A exerts cytotoxic activity against cancer cells. Hericenone A can be used for the research of cancer, such as metastatic human hepatocellular carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 126654-52-2
- Formula: C19H22O5
- Molecular Weight:330.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Hericenone A (compound 6) (5-20 μg/mL; 24 h) dose-dependently inhibits the growth of SMMC-7221 and MHCC-97H human hepatocellular carcinoma cells, with the most potent activity observed at 20 μg/mL for 24 h[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SMMC-7221, MHCC-97H
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Concentration:5, 10, 20 μg/mL
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Incubation Time:24 h
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Result:Inhibited the growth of SMMC-7221 cells in a dose-dependent manner.
Inhibited the growth of MHCC-97H cells in a dose-dependent manner.
Showed the most potent activity against both cell lines at 20 μg/mL among all tested compounds.
Chemical Information
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CAS No. 126654-52-2
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Molecular Weight 330.37
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Formula C19H22O5
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SMILES
OC1=C2C(C(OC2)=O)=CC(OC)=C1C/C=C(C)/CC(/C=C(C)\C)=O
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Structure Classification
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Initial Source
Hericium erinaceus
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)