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  3. Drug Derivative
  4. Hericenone A

Hericenone A is an isoindolinone found in the fruiting bodies of Hericium erinaceus. Hericenone A exerts cytotoxic activity against cancer cells. Hericenone A can be used for the research of cancer, such as metastatic human hepatocellular carcinoma.

For research use only. We do not sell to patients.

Hericenone A

Hericenone A Chemical Structure

CAS No. : 126654-52-2

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Hericenone A Related Antibodies

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Description

Hericenone A is an isoindolinone found in the fruiting bodies of Hericium erinaceus. Hericenone A exerts cytotoxic activity against cancer cells. Hericenone A can be used for the research of cancer, such as metastatic human hepatocellular carcinoma[1].

In Vitro

Hericenone A (compound 6) (5-20 μg/mL; 24 h) dose-dependently inhibits the growth of SMMC-7221 and MHCC-97H human hepatocellular carcinoma cells, with the most potent activity observed at 20 μg/mL for 24 h[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Hericenone A Related Antibodies

Cell Viability Assay[1]

Cell Line: SMMC-7221, MHCC-97H
Concentration: 5, 10, 20 μg/mL
Incubation Time: 24 h
Result: Inhibited the growth of SMMC-7221 cells in a dose-dependent manner.
Inhibited the growth of MHCC-97H cells in a dose-dependent manner.
Showed the most potent activity against both cell lines at 20 μg/mL among all tested compounds.
Molecular Weight

330.37

Formula

C19H22O5
CAS No.
SMILES

OC1=C2C(C(OC2)=O)=CC(OC)=C1C/C=C(C)/CC(/C=C(C)\C)=O
Structure Classification
Initial Source

Hericium erinaceus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Hericenone A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hericenone A126654-52-2Drug DerivativeDrug derivativemetastatic human hepatocellular carcinoma cellsSMMC-7221hepatocellular carcinoma cellsHericium erinaceusMHCC-97HInhibitorinhibitorinhibit

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