CI-990
CI-990 (PD-131112) is an orally active and highly selective bacterial DNA gyrase inhibitor. CI-990 is promising for research of Enterococcal infections (e.g., endocarditis, sepsis).
For research use only. We do not sell to patients.
- CAS No.: 122536-20-3
- Formula: C19H22FN5O4
- Molecular Weight:403.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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CAS No. 122536-20-3
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Molecular Weight 403.41
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Formula C19H22FN5O4
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SMILES
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4C[C@@H](NC([C@@H](N)C)=O)CC4)=N3)C1=O)O
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Synonyms
PD-131112
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Cohen MA, et al. Bacterial eradication by clinafloxacin, CI-990, and ciprofloxacin employing MBC test, in-vitro time-kill and in-vivo time-kill studies. J Antimicrob Chemother. 1998 Jun;41(6):605-14. [Content Brief]
[2]. Cohen MA, et al. In vitro and in vivo activities of clinafloxacin, CI-990 (PD 131112), and PD 138312 versus enterococci. Antimicrob Agents Chemother. 1995 Sep;39(9):2123-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)