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Cat. No.: HY-N2621

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Evodol

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Evodol is a natural product isolated from the dried and nearly ripe fruits of Euodia rutaecarpa. Evodol shows inhibitory activity against NO production. Evodol possesses larvicidal activity against the Asian tiger mosquitoes with a LC₅₀ value of 32.43 μg/ml. Evodol has the inhibitory effect on CYP3A.

For research use only. We do not sell to patients.

CAS No.: 22318-10-1
Formula: C₂₆H₂₈O₉
Molecular Weight:484.50

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Evodol Chemical Structure

CAS No.: 22318-10-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Evodol is a natural product isolated from the dried and nearly ripe fruits of Euodia rutaecarpa. Evodol shows inhibitory activity against NO production^[1]. Evodol possesses larvicidal activity against the Asian tiger mosquitoes with a LC₅₀ value of 32.43 μg/ml^[2]. Evodol has the inhibitory effect on CYP3A^[3].

IC₅₀ & Target

CYP3A

All Cytochrome P450 Isoforms :

Chemical Information

CAS No. 22318-10-1
Molecular Weight 484.50
Formula C₂₆H₂₈O₉
SMILES

C[C@]12[C@@]3([C@@H]4O3)[C@]([C@H](C5=COC=C5)OC4=O)(CC[C@]1([H])[C@]67C(C(C)(C)O[C@@]6([H])CC(OC7)=O)=C(O)C2=O)C
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Xenobiotica

Mechanism-Based Inactivation of Cytochrome P450 3A by Evodol. [Abstract]

2023 Mar;53(3):129-139. PMID: 37092795

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yang XB, et al. Limonoid constituents of Euodia rutaecarpa var. bodinieri and their inhibition on NO production in lipopolysaccharide-activated RAW264.7 macrophages. J Asian Nat Prod Res. 2013;15(10):1130-8. [Content Brief]

[2]. Liu ZL, et al. Mosquito larvicidal activity of alkaloids and limonoids derived from Evodia rutaecarpa unripe fruits against Aedes albopictus (Diptera: Culicidae).Parasitol Res. 2012 Sep;111(3):991-6. [Content Brief]

[3]. Zhao J, He J, Xu J. Mechanism-based inactivation of cytochrome P450 3A by evodol. Xenobiotica. 2023;53(3):129-139. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
Purity & Documentation
References

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Evodol

Publications Citing Use of MedChemExpress (MCE) Evodol

All Cytochrome P450 Isoforms