Homoquinolinic acid
Homoquinolinic acid is a non endogenous agonist of NMDAR2 receptor.
For research use only. We do not sell to patients.
- CAS No.: 490-75-5
- Formula: C8H7NO4
- Molecular Weight:181.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Homoquinolinic acid (HQA, 20 μM) results in a robust increase in frequency of events recorded in layer V[2].
Homoquinolinic acid (HQA) acts at the presynaptic terminal to enhance glutamate release[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 490-75-5
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Molecular Weight 181.15
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Formula C8H7NO4
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SMILES
O=C(O)CC1=CC=CN=C1C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. L P de Carvalho, et al. The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. Neurochem Int. 1996 Apr;28(4):445-52. [Content Brief]
[2]. G Woodhall, et al. NR2B-containing NMDA autoreceptors at synapses on entorhinal cortical neurons. J Neurophysiol. 2001 Oct;86(4):1644-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Homoquinolinic acid Related Classifications
HY-100802 Related Classifications
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