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Referencia número: HY-176427

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HsClpP activator-1

HsClpP activator-1 (compound 24) is a potent HsClpP activator with an EC₅₀ of 0.22 μM. HsClpP activator-1 effectively inhibits cancer cell growth with IC₅₀ values of 0.1-1 μM.

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No. CAS: 3087033-83-5
Fòrmula: C₂₃H₂₀F₅N₃O₂
Peso molecular:465.42

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

HsClpP activator-1 Chemical Structure

No. CAS: 3087033-83-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

HsClpP activator-1 (compound 24) is a potent HsClpP activator with an EC₅₀ of 0.22 μM. HsClpP activator-1 effectively inhibits cancer cell growth with IC₅₀ values of 0.1-1 μM^[1].

Chemical Information

No. CAS 3087033-83-5
Peso molecular 465.42
Fòrmula C₂₃H₂₀F₅N₃O₂
SMILES

O=C1N([C@H](CCN2N=C(C=C21)CC3=CC(F)=CC(F)=C3)CO)CC4=CC=C(C=C4)C(F)(F)F
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Tang R, et al. Design, Synthesis, and Biological Evaluation of Novel Activators of Human Caseinolytic Protease P with a Pyrazololactam Scaffold. J Med Chem. 2025 May 22;68(10):9984-10007. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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