HsClpP-ligand-1
HsClpP-ligand-1 is an intermediate derived from HsClpP ligands, and also serves as an HsClpP recruitment module for constructing mitochondria-targeted pan-PDK degraders. HsClpP-ligand-1 acts as the HsClpP ligand of the bifunctional degrader Pan-PDK degrader-1 (HY-184943).
For research use only. We do not sell to patients.
- Formula: C24H23N5O2
- Molecular Weight:413.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HsClpP |
HsClpP-ligand-1 (compound 16) is the HsClpP-targeting moiety of the bifunctional degrader Pan-PDK degrader-1 (compound A1) (HY-184943), and forms a stable ternary complex with recombinant human PDK1 and HsClpP[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 413.47
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Formula C24H23N5O2
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SMILES
OC1=C(C=CC=C1)CN2C3=NCCN3C4=C(C2=O)CN(CC4)CC5=CC=CC(C#N)=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)