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Cat. No.: HY-150539

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IAB15

IAB15 is a potent T-type calcium channel inhibitor. IAB15 can be used for epilepsy research.

For research use only. We do not sell to patients.

CAS No.: 2987139-91-1
Formula: C₁₅H₁₄F₃NO₂
Molecular Weight:297.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

IAB15 Chemical Structure

CAS No.: 2987139-91-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IAB15 is a potent T-type calcium channel inhibitor. IAB15 can be used for epilepsy research^[1].

IC₅₀ & Target

T-type calcium channel

All Calcium Channel Isoforms :

In Vitro

IAB15 (50 µM; differentiated ND7/23 cells) causes a significant reduction in the current density generated by T-type Ca²⁺ channel activation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2987139-91-1
Molecular Weight 297.27
Formula C₁₅H₁₄F₃NO₂
SMILES

CC(C1)CC(NC(C2=CC=CC(C(F)(F)F)=C2)=O)=CC1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Amaye IJ, et, al. Evaluation of potential anticonvulsant fluorinated N-benzamide enaminones as T-type Ca2+ channel blockers. Bioorg Med Chem. 2022 Jul 1;65:116766. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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IAB15

All Calcium Channel Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

IAB15 Related Classifications

HY-150539 Related Classifications