ICI-204448
Based on 1 Customer Validation
ICI-204448 is a κ-opioid agonist with limited access to the CNS, ICI-204448 can displace the binding of the kappa-opioid ligand 3H-bremazocine from guinea pig cerebellum membranes.
For research use only. We do not sell to patients.
- Purity: 98.09%
- CAS No.: 121264-04-8
- Formula: C23H27Cl3N2O4
- Molecular Weight:501.83
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 121264-04-8
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Appearance Solid
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Molecular Weight 501.83
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Formula C23H27Cl3N2O4
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Color Off-white to yellow
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SMILES
O=C(O)COC1=CC=CC(C(N(C(CC2=CC=C(Cl)C(Cl)=C2)=O)C)CN3CCCC3)=C1.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (249.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9927 mL | 9.9635 mL | 19.9271 mL | 49.8177 mL |
| 5 mM | 0.3985 mL | 1.9927 mL | 3.9854 mL | 9.9635 mL | |
| 10 mM | 0.1993 mL | 0.9964 mL | 1.9927 mL | 4.9818 mL | |
| 15 mM | 0.1328 mL | 0.6642 mL | 1.3285 mL | 3.3212 mL | |
| 20 mM | 0.0996 mL | 0.4982 mL | 0.9964 mL | 2.4909 mL | |
| 25 mM | 0.0797 mL | 0.3985 mL | 0.7971 mL | 1.9927 mL | |
| 30 mM | 0.0664 mL | 0.3321 mL | 0.6642 mL | 1.6606 mL | |
| 40 mM | 0.0498 mL | 0.2491 mL | 0.4982 mL | 1.2454 mL | |
| 50 mM | 0.0399 mL | 0.1993 mL | 0.3985 mL | 0.9964 mL | |
| 60 mM | 0.0332 mL | 0.1661 mL | 0.3321 mL | 0.8303 mL | |
| 80 mM | 0.0249 mL | 0.1245 mL | 0.2491 mL | 0.6227 mL | |
| 100 mM | 0.0199 mL | 0.0996 mL | 0.1993 mL | 0.4982 mL |
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